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A link between nuclear RNA surveillance, the human exosome and RNA polymerase I...
Almeida, Sérgio F. de; García-Sacristán, Ana; Custódio, Noélia; Carmo-Fonseca, Maria©The Author(s) 2010. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ; In eukaryotes, the production of mature messe...
Quality control of gene expression in the mammalian cell nucleus
Custódio, Noélia Maria Fernandes, 1971-Tese de doutoramento em Ciências Biomédicas (Ciências Morfológicas) apresentada à Universidade de Lisboa através da Faculdade de Medicina, 2008 ; Protein-encoding genes are transcribed in the nucleus by RNA polymerase II as precursor RNAs that undergo extensive processing before being translocated to the cytoplasm for translation by the ribosomes. This spatial and temporal separation between RNA and protein sy...
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