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Breakdown of the Inner and Outer Blood Retinal Barrier in Streptozotocin-Induce...
Carmo, Anália do; Ramos, Pedro; Reis, Aldina; Proença, Rui; Cunha-Vaz, J. G.Using vitreous fluorophotometry and quantitative fluorescence microscopy the authors studied the permeability of the blood-retinal barrier (BRB) to fluorescein in control and in 8 days streptozotocin-induced diabetic rats. ; http://www.sciencedirect.com/science/article/B6WFD-45JC7TK-T/1/ad834a7e41da87410003af7710548c3d
Microperfusion studies on the permeability of retinal vessels. A new model demo...
Murta, J. N.; Cunha-Vaz, J. G.; Sabo, C. A.; Jones, C. W.; Laski, M. E.We developed an experimental model to study the permeability of individual retinal vessels in vitro using microperfusion techniques adapted from kidney tubule studies. The retinal vessels were isolated by freehand dissection and mounted on a microperfusion apparatus. When inulin was perfused luminally, it was diluted to 80.2 +/- 2.3% of its initial concentration. However, no radioactive leak into the bath side ...
Future developments in ocular fluorophotometry instrumentation.
Leite, E B; Centro de Oftalmologia, Universidade de Coimbra, Hospitais da Universidade de Coimbra, Portugal.; Cunha-Vaz, J GThe scope of ocular fluorometry is to monitor exogenous and endogenous fluorophores in ocular tissues, in relation with ophthalmic and systemic diseases using the unique optical prospectives of the eye. The elderly population and the incidence of blindness are increasing rapidly due to more cases of diabetes, glaucoma, cataract and age-related macular degeneration. Monitoring changes in specific fluorophores in...
Methods of evaluation of retinal circulation.
Faria de Abreu, J R; Cunha-Vaz, J G; Lima, J P
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