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Brucellar Spondylodiscitis: Case Series of the Last 25 Years

Introduction: Brucellosis is an endemic zoonosis in Portugal. Brucellar spondylodiscitis is one of the most frequent focal manifestations which may cause severe sequelae despite appropriate therapy.Material and Methods: Retrospective study of patients with diagnosis of brucellar spondylodiscitis admitted to the Infectious Diseases Department of Centro Hospitalar e Universitário de Coimbra, over a 25-year period...

Chronic granulomatous disease associated with common variable immunodeficiency ...

INTRODUCTION: Chronic granulomatous disease associated with common variable immunodeficiency (GD-CVID), although well documented, is rare. Granulomatous lesions can affect several organs and are histologically indistinguishable from sarcoidosis. CLINICAL CASES: Case 1: A 39-year-old male patient with CVID, asymptomatic although with thrombocytopenia and mediastinal-hilar adenopathies. GD-CVID was diagnosed by b...

CT-guided transthoracic lung biopsy: Predictive factors of pneumothorax.

Chronic granulomatous disease associated with common variable immunodeficiency ...

INTRODUCTION: Chronic granulomatous disease associated with common variable immunodeficiency (GD-CVID), although well documented, is rare. Granulomatous lesions can affect several organs and are histologically indistinguishable from sarcoidosis. CLINICAL CASES: Case 1: A 39-year-old male patient with CVID, asymptomatic although with thrombocytopenia and mediastinal-hilar adenopathies. GD-CVID was diagnosed by b...

Malformação Quística Adenomatoideia Congénita Pulmonar. Duas Formas de Apresent...

A malformação quística adenometoideia congénita do pulmão consiste numa massa de quistos revestidos por epitélio respiratório resultante da proliferação dos bronquíolos terminais.A sua apresentação clínica é muito diversa, desde casos de morte fetal por hidrops não imune até quadros de infecções pulmonares recorrentes na infância.Os autores descrevem dois casos clínicos de malformação quística adenomatoideia co...

Encefalomielite aguda disseminada – pós-infecção por Herpes Vírus 6

RESUMO Introdução: A encefalomielite aguda disseminada (ADEM) é uma doença desmielinizante monofásica do sistema nervoso central (SNC) imunomediada. O quadro clínico inicial pode ser inespecífico, mas traduz geralmente envolvimento da substância branca em várias localizações do SNC, sendo a ressonância magnética (RM) do neuroeixo o exame complementar de diagnóstico de eleição. Caso clínico: Criança com...

Prediction of intracellular storage polymers using quantitative image analysis ...

The present study focuses on predicting the concentration of intracellular storage polymers in enhanced biological phosphorus removal (EBPR) systems. For that purpose, quantitative image analysis techniques were developed for determining the intracellular concentrations of PHA (PHB and PHV) with Nile blue and glycogen with aniline blue staining. Partial least squares (PLS) were used to predict the standard anal...

Development of image analysis methodologies to quantify intracellular PHA, poly...

In wastewater treatment plants (WWTP), enhanced biological phosphorus removal (EBPR) processes are performed by mixed cultures containing polyphosphate (PAO) and glycogen accumulating organisms (GAO). In these processes, it is of crucial importance to monitor the intracellular metabolism, namely glycogen, polyhydroxyalkanoates (PHA) and polyphosphate (polyP) inclusions, to determine its efficiency. However, tra...

Modelling of ballasted railway tracks for high-speed trains

Tese de doutoramento em Engenharia Civil ; Ballasted railway tracks are one of the most common structures travelled by high-speed trains. The high circulation speeds of these trains lead to increased vibrations in the tracks and nearby structures, which can affect the serviceability and maintenance costs of the tracks. There is a growing demand for a means of accurately predicting the performance of ballasted ...

Image analysis for automatic characterization of polyhydroxyalcanoates granules

A new monitoring approach for polyhydroxyalcanoates (PHA) granules identification and characterization based on image analysis procedures is proposed. PHA granules were analyzed by Sudan Black B (SBB) staining in an enhanced biological phosphorus removal (EBPR) system. Color images captured on an optical microscope were analyzed through quantitative image analysis. The distribution of PHA granules was estimated...