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The human umbilical cord tissue-derived MSC population UCX® promotes early moto...
Miranda JP, JP; Filipe, E; Fernandes, AS; Almeida, JM; Martins, JP; De La Fuente, A; Abal, M; Barcia, RN; Cruz, P; Cruz, H; Castro, M; Santos, JMMesenchymal stromal cells (MSCs) play an important role in tissue regeneration mainly through the secretion of trophic factors that enhance the repair of damaged tissues. The main goal of this work was to study the paracrine mechanisms by which an umbilical cord tissue-derived MSC population (UCX®) promotes the migration capacity of human dermal fibroblasts and keratinocytes, which is highly relevant for skin r...
Effect of starch-based biomaterials on the in vitro proliferation and viability...
Marques, A. P.; Cruz, H. R.; Coutinho, O. P.; Reis, R. L.The cytotoxicity of starch-based polymers was investigated using different methodologies. Poly-L-lactic acid (PLLA) was used as a control for comparison purposes. Extracts of four different starch-based blends (corn starch and ethylene vinyl alcohol (SEVA-C), corn starch and cellulose acetate (SCA), corn starch and polycaprolactone (SPCL) and starch and poly-lactic acid (SPLA70) were prepared in culture medium ...
Malnutrition during lactation as a metabolic imprinting factor inducing the fee...
Moura,A.S.; Franco de Sá,C.C.N.; Cruz,H.G.; Costa,C.L.The aim of the present study was to determine the impact of malnutrition during early postnatal life and the feeding pattern of rat offspring when adults (2 months and 1 year old). In comparison with rats normally fed during lactation, we observed that adult offspring displayed a faster process of feeding reduction when a protein-free diet was offered. In addition, we studied the concentration of insulin and le...
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