Encontrados 13 documentos, a visualizar página 1 de 2
Restless Legs Syndrome in Pregnancy: a Frequent Underdiagnosed Disorder
Keywords: Pregnancy; Pregnancy Complications Restless;Legs Syndrome.
Sustained remission from depressive-like behavior depends on hippocampal neurog...
Pinheiro, António Mateus; Pinto, Luísa; Bessa, J. M.; Morais, Mónica; Alves, N. D.; Monteiro, S.; Patrício, P.; Almeida, O. F. X.; Sousa, NunoWe thank M Carneiro and L Martins for technical assistance. AM-P, LP, MM and SM received fellowships from the Portuguese Foundation for Science and Technology (FCT). This work was supported by FCT (PTDC/SAU-NEU/105180/2008) and the ICVS. ; Impairment of hippocampal neurogenesis has been associated with the expression of depressive-like symptoms and some studies have suggested neurogenesis as a critical factor ...
Re-cycling paradigms : cell cycle regulation in adult hippocampal neurogenesis ...
Patrício, P.; Pinheiro, António Mateus; Sousa, Nuno; Pinto, LuísaSince adult neurogenesis became a widely accepted phenomenon, much effort has been put in trying to understand the mechanisms involved in its regulation. In addition, the pathophysiology of several neuropsychiatric disorders, such as depression, has been associated with imbalances in adult hippocampal neurogenesis. These imbalances may ultimately reflect alterations at the cell cycle level, as a common mechanis...
Glucocorticoid programing of the mesopontine cholinergic system
Borges, Sónia Maria de Sousa; Coimbra, Bárbara Guimarães Salazar; Cunha, Carina Isabel Soares da; Silva, Ana Paula Ventura; Pinto, LuísaStress perception, response, adaptation, and coping strategies are individually distinct, and the sequel of stress and/or glucocorticoids (GCs) is also distinct between subjects. In the last years, it has become clear that early life stress is a powerful modulator of neuroendocrine stress-responsive circuits, programing intrinsic susceptibility to stress, and potentiating the appearance of stress-related disord...
Re-cycling paradigms : cell cycle regulation in adult hippocampal neurogenesis ...
Patrício, P.; Pinheiro, António Mateus; Sousa, Nuno; Pinto, LuísaSince adult neurogenesis became a widely accepted phenomenon, much effort has been put in trying to understand the mechanisms involved in its regulation. In addition, the pathophysiology of several neuropsychiatric disorders, such as depression, has been associated with imbalances in adult hippocampal neurogenesis. These imbalances may ultimately reflect alterations at the cell cycle level, as a common mechanis...
Development and characterization of PHB-HV based 3D scaffolds for a tissue engi...
Samy, S. M.; Silva, Nuno; Pinto, Luísa; Castro, Andreia Cristiana Teixeira de; Almeida, Hugo Leite; Almeida, Armando; Sousa, Nuno; Salgado, António J.Spinal cord injury (SCI) leads to devastating neurological deficits. Several tissue engineering (TE)- based approaches have been investigated for repairing this condition. Poly (3-hydroxybutyrateco- 3-hydroxyvalerate) (PHB-HV) is found to be particularly attractive for TE applications due to its properties, such as biodegradability, biocompatibility, thermoplasticity and piezoelectricity. Hence, this report add...
Cell genesis and dendritic plasticity : a neuroplastic pas de deux in the onset...
Pinheiro, António Mateus; Patrício, P.; Bessa, J. M.; Sousa, Nuno; Pinto, LuísaBrain neuroplasticity is increasingly considered to be an important component of both the pathology and treatment of depressive spectrum disorders. Recent studies shed light on the relevance of hippocampal cell genesis and cortico-limbic dendritic plasticity for the development and remission from depressive-like behavior. However, the neurobiological significance of neuroplastic phenomena in this context is sti...
Stress-induced anhedonia is associated with hypertrophy of medium spiny neurons...
João, Bessa; Morais, Mónica; Marques, Fernanda; Pinto, Luísa; Palha, Joana Almeida; Sousa, NunoThere is accumulating evidence that the nucleus accumbens (NAc) has an important role in the pathophysiology of depression. As the NAc is a key component in the neural circuitry of reward, it has been hypothesized that anhedonia, a core symptom of depression, might be related to dysfunction of this brain region. Neuronal morphology and expression of plasticity-related molecules were examined in the NAc of rats ...
Psicopatologia, insucesso escolar e estilos educativos parentais na adolescência
Pinto, Luísa Maria Rodrigues Nunes AlmeidaDissertação de mest., Psicologia Clínica e da Saúde, Faculdade de Ciências Humanas e Sociais, Univ. do Algarve, 2013 ; O presente trabalho tem como principal objetivo analisar a relação entre os estilos educativos parentais e um conjunto de resultados desenvolvimentais em adolescentes, mais concretamente, a nível de perturbações psicopatológicas, de problemas académicos e da qualidade de vida relacionada com a...
Immuno-Golgi as a tool for analyzing neuronal 3D-dendritic structure in phenoty...
Pinto, Luísa; Pinheiro, António Mateus; Morais, Mónica; Bessa, J. M.Characterization of neuronal dendritic structure in combination with the determination of specific neuronal phenotype or temporal generation is a challenging task. Here we present a novel method that combines bromodioxyuridine (BrdU) immunohistochemistry with Golgi-impregnation technique; with this simple noninvasive method, we are able to determine the tridimensional structure of dendritic arborization and spi...
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