A three-dimensional (3D) scaffolding system for chondrocytes culture has been produced by agglomeration of cells and gelatin microparticles with a mild centrifuging process. The diameter of the microparticles, around 10 μ, was selected to be in the order of magnitude of the chondrocytes. No gel was used to stabilize the construct that maintained consistency just because of cell and extracellular matrix (ECM) ad...
Neste artigo discutem-se aspectos construtivos relacionados com as paredes divisórias tradicionais de tabique, de forma a contribuir para um conhecimento mais aprofundado sobre este tipo de elementos, que são parte integrante de um estilo de construção marcante no panorama do património construído português que imperou até inícios do século XX. Informação relativa aos materiais utilizados e às soluções construt...
Generally, the traditional building techniques uses natural and local building materials such as stone, woodand earth and, are associated to building procedures that requires small amount of energy consumption and release an expressive noxious gases to atmosphere. The development of green building techniques that help the building industry contributing to a much more sustainable world may be inspired on these t...
A região de Trás-os-Montes e Alto Douro é rica em construções de tabique. Constatou-se que grande parte destas construções antigas apresenta um avançado estado de degradação. Este facto aliado à escassez de estudos científicos relativos às construções de tabique existentes nesta região motivou a realização deste trabalho de investigação que usa doze construções como amostragem e que é focado no estudo experimen...
Our objective was to determine the presence of vascular endothelial growth factor (VEGF), matrix metalloproteinase-2 (MMP-2) and MMP-9 and specific tissue inhibitors of matrix metalloproteinase (TIMP-1 and TIMP-2) in tumor samples obtained from patients with primary breast cancer. We attempted to correlate these findings with the status of the sentinel lymph node (SLN) and clinical-pathological characteristics ...
The tabique is one of the main Portuguese traditional building techniques, which is based on raw materials as earth and wood. In general, a tabique wall is formed by a simple timber structure covered by earth. Earth has an important role in this system because it protects the internal timber structure as well as is a finishing. The Trás-os-Montes e Alto Douro is the northeast region of Portugal and it is very r...
Introduction The optimal dialysis dose for the treatment of acute kidney injury (AKI) is controversial. We sought to evaluate the relationship between renal replacement therapy (RRT) dose and outcome. Methods We performed a prospective multicentre observational study in 30 intensive care units (ICUs) in eight countries from June 2005 to December 2007. Delivered RRT dose was calculated in patients treated exclus...
O presente estudo relata uma experiência exploratória, a partir da qual procurámos intervir na temática do stress, construindo, implementando e avaliando um programa de desenvolvimento de competências de gestão de stress para jovens adultos, estudantes da Universidade de Aveiro. A revisão da literatura indica que, apesar de as Instituições do ensino superior, nacionais e internacionais, mostrarem preocupação co...
The bEuro-Lupus CohortQ is composed by 1000 patients with systemic lupus erythematosus (SLE) that have been followed prospectively since 1991. These patients have been gathered by a European consortium—the bEuro-Lupus Project GroupQ. This consortium was originated as part of the network promoted by the bEuropean Working Party on SLEQ, a working group created in 1990 in order to promote research in Europe on the...
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