A cost-effectiveness integrated methodology applied in a water resources management and sanitation project in Minho and Lima’s region (Portugal) is presented. First, environmental objectives and programmes of measures (PM) are established and priorities are identified using a cause–effect assessment matrix and a global effectiveness index. Aiming to achieve more demanding goals, some complementary actions are c...
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AIM: Retrospective analisis of the outcome in the immediate and late postoperative care of inguinal hernioplasty according to 3 mesh techniques. Matherial and Methods: From 1997 until 2005, a 9-year period, 562 inguinal hernioplasty procedures were conducted in 496 patients at Surgery I Ward of University Hospitals of Coimbra. Male gender (n=453) was the most predominant and the mean age was 59 years [16-98]. E...
Liver cirrhosis, a highly prevalent chronic disease, is frequently associated with endocrine dysfunctions, notably in the gonadal axis. We evaluated lactotroph population by immunohistochemistry, gonadotropins and prolactin by immunoradiometric assay and testosterone and estradiol by radioimmunoassay in adult male Wistar rats with cirrhosis induced by carbon tetrachloride. No significant difference in mean ± SE...
The present work was focused on a methodological assessment for defining cost-effective measures regarding to wastewater sanitation in rural areas and was carried out within the project AQUA Project – Preliminary Studies for the Water Framework Directive Implementation at the Minho and Lima’s Rivers Basins. In order to assure a good ecological and chemical status in water bodies according to Water Framework Dir...
The control of wastewater treatment plants requires an extensive monitoring programme based on physicochemical costly routine analysis. Microbial populations are well known indicators of operational conditions in biological reactors. This research was carried out by the CENTA and the University of Minho in the scope of the Erasmus programme. The aim of the work was the development of a simplified approach, base...
No presente estudo, estimou-se a abundância dos transcritos da miostatina foi estimada durante a embriogênese de galinha por análises de RT-PCR competitiva. Níveis basais de mRNA desse gene foram detectados até o estádio HH15, enquanto acúmulos significativos nesses níveis foram observados apenas no estádio HH24, seguido por redução na abundância desses transcritos a partir do estádio HH26. Tais descobertas pre...
Ionic fragmentation of the sublimated amino acid DL-proline has been studied using time-of-flight mass spectrometry and synchrotron radiation. Total ion yield and mass spectra were recorded in the 13 to 21.6 eV energy range. Partial ion yields have been calculated for the produced fragments and the results analyzed in a comparative way. Mass spectrum of proline previously obtained at 21.21 eV using photons from...
Pituitary adenomas sometimes show rapid growth and recurrence, and about one third invade the structures surrounding the sella turcica. In an attempt to determine aggressive behavior at an early stage, we used the MIB-1 antibody to identify the Ki-67 antigen. The present study was designed to evaluate pituitary adenomatous tissue in terms of secretion and proliferation and to correlate the Ki-67 index with horm...
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