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Neuronal cytoskeletal dynamic modification induced by unconjugated bilirubin

Tese de mestrado, Biologia (Biologia Molecular Humana), 2009, Universidade de Lisboa, Faculdade de Ciências ; Hyperbilirubinemia is frequently observed in the neonatal period due to the transient accumulation of unconjugated bilirubin (UCB) in serum, which in certain circumstances it may trigger neurological deficits. We have recently shown that exposure of immature hippocampal neurons to UCB, in conditions mi...