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Characterization of the inhibitor-resistant SHV β-lactamase SHV-107 in a clinic...
Manageiro, Vera; Ferreira, Eugénia; Cougnoux, Antony; Albuquerque, Luís; Caniça, Manuela; Bonnet, RichardThe clinical Klebsiella pneumoniae INSRA6884 strain exhibited nonsusceptibility to all penicillins tested (MICs of 64 to>2,048 g/ml). The MICs of penicillins were weakly reduced by clavulanate (from 2,048 to 512 g/ml), and tazobactam restored piperacillin susceptibility. Molecular characterization identified the genes blaGES-7 and a new -lactamase gene, blaSHV-107, which encoded an enzyme that differed from SH...
Data: 2012
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Origem: Repositório Científico do Instituto Nacional de Saúde
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