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Myocardial Dysfunction and Neurohumoral Activation Without Remodeling in the Le...
Lourenço, AP; Roncon-Albuquerque R, Jr.; Brás-Silva, C; Faria, B; Wieland, J; Henriques-Coelho, T; Correia-Pinto, J; Leite-Moreira, AFIn monocrotaline (MCT)-induced pulmonary hypertension (PH), only the right ventricle (RV) endures overload, but both ventricles are exposed to enhanced neuroendocrine stimulation. To assess whether in long-standing PH the left ventricular (LV) myocardium molecular/contractile phenotype can be disturbed, we evaluated myocardial function, histology, and gene expression of autocrine/paracrine systems in rats with ...
Data: 2006
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Origem: Repositório Aberto da Universidade do Porto
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