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Bacterial cellulose : long-term biocompatibility studies
Pértile, Renata Aparecida Nedel; Moreira, Susana; Costa, Rui M. Gil da; Correia, Alexandra; Guardão, Luísa; Gartner, Fátima; Vilanova, ManuelThe bacterial cellulose (BC) secreted by G. xylinus is a network of pure cellulose nanofibers, which has high crystallinity, wettability and mechanical strength. These characteristics make BC an excellent material for tissue engineering constructs, noteworthy for artificial vascular grafts. In this work, the in vivo biocompatibility of BC membranes produced by two G. xylinus strains was analyzed through histolo...
In vivo biocompatibility and biodegradability of dextrin-based hydrogels
Moreira, Susana; Costa, Rui M. Gil da; Guardão, Luisa; Gartner, Fátima; Vilanova, Manuel; Gama, F. M.The in vivo biocompatibility of dextrin hydrogels obtained by polymerization of dextrin-hydroxyethylmethacrylate (dextrin-HEMA) and dextrin-vinyl acrylate (dextrin-VA) are reported in this work. The histological analysis of subcutaneous implants of these hydrogels, featuring inflammatory and reabsorption events, were carried out over a 16-week period in mice. The dextrin-HEMA hydrogel was quickly and completely...
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