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In vitro and in vivo chitosan membranes testing for peripheral nerve reconstruc...
Simões, M J; Gärtner, A; Shirosaki, Y; Gil da Costa, R M; Cortez, P P; Gartnër, F; Santos, J D; Lopes, M A; Geuna, S; Varejão, A S PTissue regeneration over a large defect with a subsequent satisfactory functional recovery still stands as a major problem in areas such as nerve regeneration or bone healing. The routine technique for the reconstruction of a nerve gap is the use of autologous nerve grafting, but still with severe complications. Over the last decades several attempts have been made to overcome this problem by using biomaterials...
DNA repair-related genes in sugarcane expressed sequence tags (ESTs)
Costa,R.M.A.; Lima,W.C.; Vogel,C.I.G.; Berra,C.M.; Luche,D.D.; Medina-Silva,R.; Galhardo,R.S.; Menck,C.F.M.; Oliveira,V.R.There is much interest in the identification and characterization of genes involved in DNA repair because of their importance in the maintenance of the genome integrity. The high level of conservation of DNA repair genes means that these genetic elements may be used in phylogenetic studies as a source of information on the genetic origin and evolution of species. The mechanisms by which damaged DNA is repaired ...
Modelling the kinetics of water loss during potato frying with a compartmental ...
Costa, R. M.; Oliveira, F.A.R.The complexity of the frying process impairs the development of mechanistic models to describe water losses. Empirical models, though lacking a theoretical basis, may provide a suitable and simpler alternative. In this work it was found that a two parallel compartments model (core and edge compartments), with a time-dependent boundary condition, could be successfully applied for this purpose. The model showed a...
Multisubstrate Michaëlis-Menten kinetics: Explicit dependence of substrate conc...
Costa, R. M.; Malcata, F. X.The problem of expressing the concentration of each of a set of substrates in a batch reactor as an explicit function of time in the case the multisubstrate system is described by Michaelis-Menten kinetics is tackled in dimensionless form via expansion as a Taylor series. The general analytical form for the coefficients of this expansion is obtained and estimates of the average quadratic error associated with i...
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