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Assessment of sediment contamination in an impacted estuary: differential effec...

Conferência realizada em Lisboa, de 6-9 November de 2013 ; Estuarine pollution is reflected in the concentration of toxicants in sediments, depending on their geochemical properties, since sediments trap substances from the water column, either dissolved or bound to suspended matter. However, determining risk of sediment contaminants to biota has many constraints. For such reason, integrative approaches are ke...

Building a reference DNA barcode library for marine amphipods of Portugal

From DNA barcodes to monitoring of amphipod communities : status and relevance ...

Body fat and cholecalciferol supplementation in elderly homebound individuals

Vitamin D deficiency, observed mainly in the geriatric population, is responsible for loss of bone mass and increased risk of bone fractures. Currently, recommended doses of cholecalciferol are advised, but since there are few studies evaluating the factors that influence the serum levels of 25-hydroxyvitamin D (25(OH)D) following supplementation, we analyzed the relationship between the increase in serum 25(OH...

The use of protein structure/activity relationships in the rational design of s...

The recombinant heat shock protein (18 kDa-hsp) from Mycobacterium leprae was studied as a T-epitope model for vaccine development. We present a structural analysis of the stability of recombinant 18 kDa-hsp during different processing steps. Circular dichroism and ELISA were used to monitor protein structure after thermal stress, lyophilization and chemical modification. We observed that the 18 kDa-hsp is extr...