Encontrados 22 documentos, a visualizar página 1 de 3

Perceção da vulnerabilidade ao stress em função do estatuto laboral num context...

Este estudo teve por objetivo analisar a vulnerabilidade ao stress em sujeitos que se encontram desempregados. O trabalho foi realizado com uma amostra portuguesa de sujeitos empregados e desempregados (N=180). O desenho do estudo é do tipo transversal, sendo os sujeitos avaliados num único momento. Utilizou-se um questionário sócio-demográfico e o 23QVS-Questionário de Vulnerabilidade ao Stress. A hipótese 1 p...

Plasmid DNA hydrogels for biomedical applications

In the last few years, our research group has focused on the design and development of plasmid DNA (pDNA) based systems as devices to be used therapeutically in the biomedical field. Biocompatible macro and micro plasmid DNA gels were prepared by a cross-linking reaction. For the first time, the pDNA gels have been investigated with respect to their swelling in aqueous solution containing different additives. F...

Functional biopolymer-based matrices for modulation of chronic wound enzyme act...

Collagen, collagen/hyaluronic acid (HA) and collagen/HA/chitosan (CS) sponges loaded with epigallocatechin gallate (EGCG), catechin (CAT) and gallic acid (GA) were developed and evaluated as active chronic wound dressings. Their physico-mechanical properties, biostability, biocompatibility and ability to inhibit in vitro myeloperoxidase (MPO) and collagenase—major enzymes related with the persistent inflammatio...

Adhesion of adipose-derived mesenchymal stem cells to patterned protein-glycosa...

Publicado em "Journal of Tissue Engineering and Regenerative Medicine", vol. 7, supp. 1 (2013) ; Proteins and glycosaminoglycans (GAGs) are the main constituents of the extracellular matrix (ECM). Until very recently, GAGs were considered as pure structural components while proteins have been associated with crucial cell signalling processes. Nowadays, it is well accepted that these two ECM components act in s...

Plano de comunicação digital para a eficiência energética

Projeto de Mestrado em Marketing / Classificação JEL: D83, Q40, M37 ; A Eficiência Energética pode contribuir para a redução das emissões mundiais de dióxido de carbono em 72% até 2020, segundo as previsões do World Energy Outlook (IEA, 2011). Simultaneamente, a Comunicação Digital e o Marketing Verde revelam-se como duas tendências de importância crescente para os consumidores, que são cada vez mais exigentes...

Sulfation degree of glycosaminoglycans triggers distinct cytoskeleton organisat...

Glycosaminoglycans (GAGs) comprise the closest cellular environment: they are building elements of the ECM and can be also found on cells surface. Their biological activity depends on several parameters among which the negative charge is of prime importance[1]. This charge is generally associated with the presence of sulfate groups (-OSO3H). Sulfation is a dynamic modification: it can occur at various positions...

Psychosocial factors associated with embryo donation for scientific research in...

Sulfonic groups induce formation of filopodia in mesenchymal stem cells

Glycosaminoglycans (GAGs) are an integral part of the extracellular matrix and glycocalix, i.e. the closest cellular environment. They are abundant in –OH groups and their bioactivity is also associated with the presence of negatively charged –SO3H functionalities. Therefore, we have investigated and discussed the influence of these functional units on mesenchymal stem cells (MSCs) behaviour using single compon...

GAGs-thiolated chitosan assemblies for chronic wounds treatment : control of en...

Multilayered polyelectrolyte coatings comprising thiolated chitosan (TC) and glycosaminoglycans (GAGs), chondroitin sulphate and hyaluronic acid, were built using a layer-by-layer approach. The surface activity of these coatings for binding and inhibition of enzymes related to chronic inflammation, such as collagenase and myeloperoxidase, was assessed. The build-up of five bi-layers of TC/GAGs onto gold surface...

Estimação de poluentes em sistemas urbanos de drenagem de águas pluviais

Dissertação de mestrado integrado em Engenharia Civil ; O crescimento urbano verificado nas últimas décadas tem contribuído para a degradação da qualidade da água em cursos naturais. As superfícies impermeáveis, características de áreas urbanas, impedem em larga escala a infiltração da precipitação no solo e, durante o período seco, estão sujeitas à acumulação de poluentes, devido à concentração de atividades ...