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Nanoencapsulation of bovine lactoferrin for food and biopharmaceutical applicat...

Balcão, V. M.; Costa, Carla Isabel; Matos, Carla M.; Moutinho, C.; Amorim, Manuela; Pintado, Manuela E.; Gomes, Ana P.; Vila, Marta M.; Teixeira, J. A.

Lactoferrin has for long captured the interest of many researchers as a natural compound with a wide variety of uses. Lactoferrin is a monomeric, iron-binding 80 kDa glycoprotein, and appears to be the subfraction of whey with the best documented antiviral, antimicrobial, anticancer and immune modulating/enhancing effects. It belongs to the family of transferrin proteins, and serves to control iron levels in bo...


Self-assembled mannan nanogel : cytocompatibility and cell localization

Ferreira, Sílvia A.; Carvalho, Vera; Vilanova, Manuel; Costa, Carla Isabel; Teixeira, João P.; Gama, F. M.

Amphiphilic mannan, produced by the Michael addition of hydrophobic 1-hexadecanethiol to vinyl methacrylated mannan, self-assembles in aqueous medium through hydrophobic interactions among alkyl chains. Resultant nanogel is stable, spherical, polydisperse, with 50–140 nm mean hydrodynamic diameter depending on the polymer degree of substitution, and nearly neutral negative surface charge. No cytotoxicity of man...


Dificuldades, diagnósticos e tratamento na síndrome custing cíclica, a propósit...

Costa, Carla Isabel da Silva Neves da

Mestrado Integrado em Medicina ; Master Degree in Medicine


A multiple emulsion formulation of bacteriophage encapsulated in lipid nanovesi...

Balcão, V. M.; Azevedo, André Filipe; Castro, Luís Miguel; Costa, Carla Isabel; Santos, Sílvio; Matos, Carla Manuela; Moutinho, C.; Teixeira, J. A.


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia