Encontrados 2 documentos, a visualizar página 1 de 1
Overexpression of tumour-associated carbohydrate antigen sialyl-Tn in advanced ...
Ferreira, José Alexandre; Videira, Paula; Lima, Luís; Pereira, Sofia; Silva, Mariana; Carrascal, Milene; Severino, Paulo; Fernandes, ElisabeteLittle is known on the expression of the tumour-associated carbohydrate antigen sialyl-Tn (STn), in bladder cancer. We report here that 75% of the high-grade bladder tumours, presenting elevated proliferation rates and high risk of recurrence/progression expressed STn. However, it was mainly found in non-proliferative areas of the tumour, namely in cells invading the basal and muscle layers. STn was also found ...
A delecção do gene TP53 e a acumulação do p53 (AB-240) são importantes na dete...
Pereira, Sofia; Costa, Céu; Lameiras, Catarina; Amaro, Teresina; Bento, Maria; Koch, Alberto; Santos, Lúcio LaraTP53 gene deletions or mutations were related to more aggressiveness in invasive and in situ bladder tumors. However, its prognostic value in the superficial ones is not well defined. Sixty-two cases with low-grade superficial urothelial cell carcinomas (uccs) were studied. twenty-two suffered recurrence and 10 of these progressed. FiSH for TP53 detection and immunohistochemistry for p53 with both Do7 and Ab-24...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||