The Porto settlement (Northwest Portugal, Iberian Peninsula) was originally built in the twelfth century and has been developed on granitic hill slopes of the Douro riverside, being one of the oldest cities in Europe. In the urban area of Porto, the second most important city of the Portuguese mainland, there is a population of about 216,000 inhabitants. This study highlights the importance of urban speleologic...
Circadian timing is structured in such a way as to receive information from the external and internal environments, and its function is the timing organization of the physiological and behavioral processes in a circadian pattern. In mammals, the circadian timing system consists of a group of structures, which includes the suprachiasmatic nucleus (SCN), the intergeniculate leaflet and the pineal gland. Neuron gr...
O trabalho relata a experiência de um processo de ensino-aprendizagem baseado na abordagem por competências. O detalhamento desse processo de ensino revela a preocupação dos autores com a pouca ocorrência de estudos sobre o desenvolvimento prático do tema competências no âmbito das práticas educativas e, apontam para a necessidade de produção de mais estudos nessa dimensão.
The binding of chlorpromazine (CPZ) and hemin to bovine serum albumin was studied by the fluorescence quenching technique. CPZ is a widely used anti-psychotic drug that interacts with blood components, influences bioavailability, and affects function of several biomolecules. Hemin is an important ferric residue of hemoglobin that binds within the hydrophobic region of albumin with high specificity. Quenching of...
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