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Evaluation of the 1329L as a candidate to delete for production of a viral atte...

Tese de mestrado em Microbiologia Clínica, apresentada à Faculdade de Medicina da Universidade de Lisboa, 2009 ; Viruses are obligate intracellular parasites and, as a consequence of many years of coevolution with their hosts, have evolved genes/strategies to manipulate and/or evade host cell biology and immune responses. Many of these viral evasion genes code for proteins that are non-essential for virus repl...