Encontrados 3 documentos, a visualizar página 1 de 1
Efeitos da radiação em culturas celulares normais de amniócitos humanos e macró...
Santos, A. C.; Lopes, M. C.; Pinto, M.; Carreira, I.; Aleixo, I.; Rolo, I.; Neves, L.; Costa, R.; Cordeiro, R.; Ferreira, C.; Almeida, G.; Tavares, H.Resumo do poster apresentado ao XII Congresso Nacional de Medicina Nuclear, 12-14 Novembro 2009, Mealhada
A novel hot-plate test sensitive to hyperalgesic stimuli and non-opioid analgesics
Lavich,T.R.; Cordeiro,R.S.B.; Silva,P.M.R.; Martins,M.A.It is widely accepted that the classical constant-temperature hot-plate test is insensitive to cyclooxygenase inhibitors. In the current study, we developed a variant of the hot-plate test procedure (modified hot-plate (MHP) test) to measure inflammatory nociception in freely moving rats and mice. Following left and right hind paw stimulation with a phlogogen and vehicle, respectively, the animals were placed i...
Enterolobin induces rat paw oedema independently of PAF-acether
Castro Faria Neto,H. C.; Cordeiro,R. S. B.; Martins,M. A.; Correia da Silva,A. C. V.; Bozza,P. T.; Sousa,M. V.; Morhy,L.The potential participation of PAF-acether (PAF) on the paw oedema triggered by enterolobin was investigated. Intraplantar injections of enterolobin )5-20 µg/paw) yielded a dose response curve for edema which appeared after 30 min, peaked in the interval between 2-4 h and faded after 24h. The pre-treatment with BN 52021, but not with other PAF antagonists such as PCA 4248 or WEB 2086, significantly blocked ent...
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