Vanadium is a heavy metal present in the Earth’s crust whose utilization by the industry of steel, pesticides and paints has increased in the last years, contributing to increase of its environmental level, making it a pollutant. Several studies reveal that vanadium causes genotoxic and mutagenic effects, although may be beneficial for some organisms, exerting antitumor effects by activating the signaling pathw...
The environmental levels of vanadium, a heavy metal widely used in industry of steel, pesticides and paints has increase in the last years. Several authors has described this metal as genotoxic and mutagenic, although at low levels of exposition it can present beneficial effects for some organisms as antitumoral agent that activates detoxification mechanisms or signaling pathway of apoptosis. Consequently, the ...
Vanadium pentoxide, V2O5 (V5+) behaves as powerful oxidizing agent which participates in free radicals generation. Although some biological studies reveals that vanadium compounds have mutagenic and genotoxic effects, other authors reveal that vanadium exerts antitumoral effects by activating signaling pathways leading to apoptosis or inducing xenobiotic metabolizing enzymes which degrade active carcinogens. In...
Vanadium pentoxide mainly used as catalyst in sulphuric acid, maleic anhydride and ceramics industry, is a pollutant watering redistributed around the environment. Research on biological influence of vanadium pentoxide has gained major importance because it exerts toxic effects on a wide variety of biological systems. In this work we intent to evaluate the effects of vanadium pentoxide ranging from 0 to 2 mM in...
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