Neurons are highly polarized cells, and the local synthesis of proteins at the synapse requires mechanisms to deliver specific transcripts to dendrites. The transport of newly synthesized mRNAs from the nucleus to dendrites is conducted by RNA granules that allow the delivery and stabilize transcripts. These granules are disassembled in response to synaptic stimulation and this is thought to release the mRNAs f...
Financiadores do RCAAP | |||||||
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