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Preparation and characterization of flurbiprofen-loaded poly(3-hydroxybutyrate-...
Coimbra, Patrícia A.; Sousa, Hermínio C. de; Gil, Maria H.Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microspheres containing flurbiprofen were prepared by an oil-in-water emulsion solvent evaporation method, in order to develop a particulate drug delivery system for localized administration. A response surface method (RSM) using a central composite design was employed to evaluate the effect of the poly(vinyl alcohol) (PVA) (%, w/v) concentration in the aqueou...
Data: 2008
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Origem: Estudo Geral - Universidade de Coimbra
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