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Unravelling the behaviour of curcumin nanoemulsions during in vitro digestion: ...

Pinheiro, A. C.; Lad, M.; Silva, Hélder D.; Coimbra, Manuel A.; Boland, M.; Vicente, A. A.

Oil-in-water nanoemulsions containing curcumin were prepared through high-pressure homogenization using corn oil and three different emulsifiers: Tween 20 (non-ionic), Sodium Dodecyl Sulphate (SDS, anionic) and DodecylTrimethylAmmonium Bromide (DTAB, cationic). A human gastric simulator was used as the in vitro digestion model (in which the stomach, duodenum, jejunum and ileum steps were performed) to evaluate ...


Pectic polysaccharides from the infusions of P. tridentatum, F. angustifolia an...

Martins, Vitor Manuel Ramalheira; Francisco, Vera; Cruz, Maria T.; Batista, Maria T.; Coimbra, Manuel A.

In Tras-os-Montes region (Portugal), the small shrub (Pterospartum tridentatum) , the narrow-leafed ash (Fraxinus angustifolia), and the apple mint (Mentha suaveolens) are vegetable species frequently used in the preparation of infusions for medicinal purposes. According to the popular tradition, the infusions prepared from P. tridentatum, F. angustifolia and M. suaveolens protect against diabetes, hypertension...

Data: 2013   |   Origem: Biblioteca Digital do IPB

Pectic polysaccharides from the infusions of P. tridentatum, F. angustifolia an...

Martins, Vitor Manuel Ramalheira; Ferreira, Isabel V.; Cruz, Maria T.; Batista, Maria T.; Coimbra, Manuel A.

In Trás-os-Montes region (Portugal), the small shrub (Pterospartum tridentatum), the narrow-leafed ash (Fraxinus angustifolia), and the apple mint (Mentha suaveolens) are vegetable species used in the preparation of infusions for medicinal purposes, such as protection against diabetes, hypertension, high levels of cholesterol and uric acid [1]. These infusions contain several types of polysaccharides, such as p...

Data: 2013   |   Origem: Biblioteca Digital do IPB

Interactions between K-carrageenan and chitosan in nanolayered coatings - Struc...

Pinheiro, A. C.; Bourbon, A. I.; Medeiros, Bartolomeu G. de S.; Silva, Luis Henrique Mendes da; Silva, Maria do Carmo Hespanhol da

The interactions between -carrageenan and chitosan, two oppositely charged polysaccharides, have been investigated through microcalorimetric and quartz crystal microbalance measurements. Microcalorimetric measurements show that -carrageenan/chitosan interaction is an exothermic process and that the alternate deposition of -carrageenan and chitosan results in the formation of a nanolayered coating mainly due ...


Palmitoylation of xanthan polysaccharide for self-assembly microcapsule formati...

Mendes, Ana Carina; Baran, Erkan Türker; Nunes, Cláudia; Coimbra, Manuel A.; Azevedo, Helena S.; Reis, R. L.

Hydrophobized polysaccharides have emerged as a promising strategy in the biomedical field due to the versatility to design functional structures through the spontaneous self-assembly in cell-friendly conditions. Based on this concept, xanthan, a bacterial extracellular polysaccharide with potential as encapsulating matrix, was conjugated with hydrophobic palmitoyl groups to obtain an amphiphilic system able to...


Κ-carrageenan/chitosan nanolayered coating for controlled release of a model bi...

Pinheiro, A. C.; Bourbon, A. I.; Quintas, Mafalda A. C.; Coimbra, Manuel A.; Vicente, A. A.

Multilayer nanocoatings composed of κ-carrageenan, a sulphated anionic polysaccharide, and chitosan, a cationic polysaccharide, were produced by layer-by-layer deposition. The model cationic compound Methylene Blue (MB) was incorporated in different positions of the nanolayered coating and its loading and release behavior was evaluated. UV–VIS spectroscopy and quartz crystal microbalance analysis showed that th...


Chemical characterization and antioxidant activity of sulfated polysaccharide f...

Souza, B. W. S.; Cerqueira, M. A.; Bourbon, A. I.; Pinheiro, A. C.; Martins, Joana; Teixeira, J. A.; Coimbra, Manuel A.; Vicente, A. A.

Hydrocolloids from seaweeds have interesting functional properties, such as antioxidant activity and gelling ability. A polysaccharide was isolated by aqueous extraction at 90 C from the red seaweed Gracilaria birdiae (Gb), with a yield of 27.2% of the seaweed dry weight. The sulfate content of the polysaccharide was 8.4% and the main sugars present were galactose (65.4 mol%), 3,6-anhydrogalactose (25.1 mol%) a...


Isolation and characterization of polysaccharides from Fraxinus angustifolia in...

Martins, Vitor Manuel Ramalheira; Francisco, Vera; Cruz, Maria T.; Coimbra, Manuel A.

In folk medicine there is a great variety of plants that are used for as infusions, such as Camellia sinensis and Matricaria recutita. Despite the reported biological activities and health benefits of these infusions, most of the knowledge achieved so far is based on folk tradition passed over several generations, without a sound scientific basis. In Trás-os-Montes region, the dried leaves of the narrow-leafed...

Data: 2012   |   Origem: Biblioteca Digital do IPB

Isolation and characterization of polysaccharides from Fraxinus angustifolia in...

Martins, Vitor Manuel Ramalheira; Coimbra, Manuel A.

In folk medicine there is a great variety of plants that are used for as infusions, such as Camellia sinensis and Matricaria recutita. Despite the reported biological activities and health benefits of these infusions, most of the knowledge achieved so far is based on folk tradition passed over several generations, without a sound scientific basis. In Trás-os-Montes region, the dried leaves of the narrow-leafed...

Data: 2012   |   Origem: Biblioteca Digital do IPB

Isolation and characterization of polysaccharides from Fraxinus angustifolia in...

Martins, Vitor Manuel Ramalheira; Coimbra, Manuel A.

In folk medicine there is a great variety of plants that are used for as infusions, such as Camellia sinensis and Matricaria recutita. Despite the reported biological activities and health benefits of these infusions [1,2], most of the knowledge achieved so far is based on folk tradition passed over several generations, without a sound scientific basis. In Trás-os-Montes region, the dried leaves of the narrow-l...

Data: 2012   |   Origem: Biblioteca Digital do IPB

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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia