Due to widespread and indiscriminate use of conventional antibiotics, bacteria have acquired a resistant phenotype in response to those antimicrobials pressure. Therefore, microbial infections associated with biofilms have become hard to treat with conventional therapy. The development of microbial drug resistance and drugrelated toxicity has promoted the search for new alternatives, to control, mostly, healthc...
Pseudomonas aeruginosa is an important cause of acute nosocomial and biofilm-associated infections that are often difficult to eradicate. The increase of antimicrobial resistance, especially in sessile microorganisms, has promoted the search for new alternatives, as natural products, to control biofilm infections. Essential oils are natural, volatile, and complex compounds produced by aromatic plants as seconda...
As biofilm research has developed into a data-intensive discipline, the need for su1table bioinformatics approaches became compelling to manage and validate individual experiments, and also to execute intra- and inter-laboratory large-scale comparisons. However, collection and gathering of data is often troublesome, as biofilm data is widespread across ad hoc, non-standardized and private individual files. Biof...
Dissertação de mestrado em Engenharia Clínica ; Microorganisms have been showing augmented resistance towards antimicrobials, being microbial resistance, nowadays, one of the biggest problems of public health. Thus, there is an increasing interest in the development of new strategies of microbial control, namely the ones based on natural products, especially from plants, such as lectins. So, it is of utmost im...
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