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NOD2 gene mutations in ulcerative colitis: useless or misunderstood?

PURPOSE: NOD2 mutations have been linked to an increased risk of Crohn's disease and to some of its phenotypes. The association between NOD2 mutations and susceptibility to ulcerative colitis (UC) remains somewhat controversial and potential correlations between these mutations and UC phenotype have not been studied. AIM: To assess whether NOD2 mutations are a risk factor for UC in Portugal and if there are any...

Ileal intussusception due to a parasite egg: A case report.

Ileal intussusception is the invagination of the small intestine within itself and accounts for 1% of cases of acute obstruction. However, physicians do not initially consider intussusception as a possible diagnosis of obstruction due to its rarity in adults. Herein, we report the case of a 22-year-old male who was admitted to the Emergency Department with continuous abdominal pain. Ultrasonography and computed...

Documento de Consenso Sobre Codificação de Exames de Ressonância Magnética Card...

Um dos obstáculos a uma utilização mais frequente e apropriada da ressonância magnética cardíaca (RMC) em Portugal tem sido a ausência de códigos específicos que descrevam adequadamente os exames tal como são efetuados actualmente. Este documento de consenso fornece recomendações para a atualização e uniformização dos códigos empregues na RMC. São igualmente feitas recomendações quanto às técnicas e códigos a u...

Cor Triatriatum num Adulto Assintomático. Diagnóstico por AngioTC Cardíaca

Treatment of Severe Nail Psoriasis with Etanercept

Narcolepsia – a propósito de um caso clínico

A Narcolepsia é uma doença crónica cuja causa exacta continua ainda por esclarecer. Caracteriza-se por sintomas cardinais como sonolência diurna excessiva e cataplexia, reveste-se de algumas especificidades a nível poligráfico e pode estar associada a determinados marcadores imunogenéticos. Determina habitualmente importantes consequências no funcionamento global e na adaptação psicossocial do indivíduo, afecta...

Case 136: intraductal papillary mucinous tumor (main duct type) of the pancreas

Experimental toxoplasmosis in Balb/c mice. Prevention of vertical disease trans...

In a study of congenital transmission during acute infection of Toxoplasma gondii, 23 pregnant Balb/c mice were inoculated orally with two cysts each of the P strain. Eight mice were inoculated 6-11 days after becoming pregnant (Group 1). Eight mice inoculated on the 10th-15th day of pregnancy (Group 2) were treated with 100 mg/kg/day of minocycline 48 h after inoculation. Seven mice inoculated on the 10th-15th...

Snoring in Portuguese primary school children

OBJECTIVE: To determine the prevalence of snoring and its potential associations with sleep problems, such as daytime symptoms, medical conditions, school performance, and behavioral disturbances in Portuguese children attending primary school. METHODS: A previously validated questionnaire was sent to the parents of 1381 children attending primary schools in a parish of Coimbra, Portugal. To assess behavioral d...