Objectives: Multidrug-resistant (MDR) plasmids together with clonal dissemination of resistant isolates are possibly the most successful combination of factors contributing to the spread of antibiotic resistance genes. Our aim was to identify clones associated with multidrug-resistance among human and dolphin isolates, in order to evaluate zoonotic potential and risk. Methods: Sixty two MDR human Escherichia co...
A rapid development of plasmid-mediated resistance to extended-spectrum cephalosporins has been observed in Enterobacteriaceae worldwide, predominantly due to the dissemination of extended-spectrum beta-lactamases (ESBL) and plasmid-mediated AmpC beta-lactamases (PMAB). The aim of the present study was to evaluate the extension of ESBL- and PMAB-producing E. coli strains isolated from different animal origins ...
Salmonella enterica is a zoonotic bacteria transmitted through the food chain and isolates harbouring extended-spectrum beta-lactamases (ESBLs) have emerged worldwide during the last decade, with the CTX-M group being particularly important. The aim of the present study was to determine the antimicrobial susceptibility of S. enterica strains isolated from broilers and food of animal origin and to characterize E...
Multidrug-resistant (MDR) plasmids together with clonal dissemination of resistant isolates are possibly the most successful combination of factors contributing to the spread of antibiotic resistance genes. Our aim was to identify clones associated with multidrug-resistance among human and dolphin isolates, in order to evaluate zoonotic potential and risk. Sixty two MDR human Escherichia coli isolates were rand...
Background: The recent spread of plasmid-located CTX-M-ESBL-encoding genes is a serious threat to the clinical efficacy of expanded-spectrum cephalosporins. This study proposes to identify the epidemiology of plasmid-mediated CTX-M-encoding genes between an Escherichia coli strain isolated from a dolphin and several E. coli strains of human origin and, explain the responsible mechanism and reservoirs of current...
Poster P1359 ; Background: Plasmid-mediated quinolone resistance (PMQR) is increasingly identified worldwide in Enterobacteriaceae. The aim of this study was to evaluate the extension of PMQR in isolates from animals in Portugal. Methods: We screened 186 Enterobacteriaceae isolates for the presence of PMQR determinants, identified at National Laboratory of Veterinary Research (2008-2009). A total of 92 Salmone...
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