Encontrados 15 documentos, a visualizar página 1 de 2
Migration of “bioabsorbable” screws in ACL repair. How much do we know? a syste...
Pereira, H.; Correlo, V. M.; Correia, Joana Silva; Oliveira, Joaquim M.; Reis, R. L.; Mendes, João EspregueiraPurpose Although bioabsorbable screws promise to degrade within months up to several years after implantation, often this does not happen. In fact, other problems such as screw breakage, tunnel enlargement, allergic or foreign body reactions, cyst or abscess formation, and delayedmigration of ‘‘biodegradable’’ screws have been reported. This study aims to provide relevant basic science knowledge and recent insi...
Silk-Fibroin/Methacrylated Gellan Gum Hydrogel as an novel scaffold for applica...
Pereira, H.; Correia, Joana Silva; Yan, Leping; Caridade, S. G.; Frias, A. M.; Oliveira, A. L.; Mano, J. F.; Oliveira, Joaquim M.Introduction: Knee meniscus injury is highly prevalent and there is a demand for new cost-effective treatment solutions. Tissue engineering (TE) and regenerative medicine strategies using acellular scaffolds are being used in clinical application for total or partial meniscus replacement [1]. Although this strategy has been considered as a safe and promising approach, progressive volume reduction of the implant...
On the development of advanced methodologies to assist on the diagnosis of huma...
Leal, Ana; Silva, Filipe Samuel; Flores, Paulo; Pereira, H.; Mendes, João EspregueiraThe main purpose of this investigation is to present a preliminary study on the development of advanced methodologies to assist on the diagnosis of human articulations pathologies. In this process, a biomechanical approach is considered to characterize the patellofemoral joint. The present research work involves two distinct scientific domains, respectively, engineering and health sciences, and arises as a resu...
Segmental characterization of the cellular density of human knee meniscus
Cengiz, I. F.; Pereira, H.; Mendes, João Espregueira; Pêgo, José M.; Oliveira, Joaquim M.; Reis, R. L.Publicado em "Journal of Tissue Engineering and Regenerative Medicine", vol. 7, supp. 1 (2013) ; Meniscus is a fibrocartilaginous tissue that has an important role in biomechanics of the knee joint. Fibrochondrocytes and fibroblast-like cells are the two main cell populations present in the meniscus. Meniscus is distinguished into two regions: avascular and vascular region. Cellularity varies within the human ...
Erratum to: Migration of “bioabsorbable” screws in ACL repair. How much do we k...
Pereira, H.; Correlo, V. M.; Correia, Joana Silva; Oliveira, Joaquim M.; Reis, R. L.; Mendes, João EspregueiraPurpose Although bioabsorbable screws promise to degrade within months up to several years after implantation, often this does not happen. In fact, other problems such as screw breakage, tunnel enlargement, allergic or foreign body reactions, cyst or abscess formation, and delayedmigration of ‘‘biodegradable’’ screws have been reported. This study aims to provide relevant basic science knowledge and recent insi...
New tools for diagnosis, assessment of surgical outcome and follow-up
Pereira, H.; Sevivas, Nuno; Pereira, Rogério; Monteiro, Alberto; Oliveira, Joaquim M.; Reis, R. L.; Mendes, João EspregueiraObjective evaluation of antero-posterior and rotatory laxity of the knee is a critical issue in anterior cruciate ligament (ACL) research. Th is is essential to allow surgeons to rigorously evaluate the outcome of the diff erent available techniques. Furthermore it will make it possible to carry out advance predictions of which patients can benefi t from a particular approach, i.e. partial reconstructions, sing...
Assessment of rotatory laxity in anterior cruciate ligamentdeficient knees using...
Mendes, João Espregueira; Pereira, H.; Sevivas, Nuno; Passos, Cláudia; Vasconcelos, José C.; Monteiro, Alberto; Oliveira, Joaquim M.; Reis, R. L.Purpose Objective evaluation of both antero-posterior translation and rotatory laxity of the knee remains a target to be accomplished. This is true for both preoperative planning and postoperative assessment of different ACL reconstruction emerging techniques. The ideal measurement tool should be simple, accurate and reproducible, while enabling to assess both ‘‘anatomy’’ and ‘‘function’’ during the same examin...
Osteochondral transplantation using autografts from the upper tibio-fibular join...
Mendes, João Espregueira; Pereira, H.; Sevivas, Nuno; Varanda, Pedro; Silva, Manuel Vieira da; Monteiro, Alberto; Oliveira, Joaquim M.; Reis, R. L.Purpose Treatment of large cartilage lesions of the knee in weight-bearing areas is still a controversy and challenging topic. Autologous osteochondral mosaicplasty has proven to be a valid option for treatment but donor site morbidity with most frequently used autografts remains a source of concern. This study aims to assess clinical results and safety profile of autologous osteochondral graft from the upper ti...
Advanced mimetic materials for meniscus tissue engineering : targeting segmenta...
Correia, Joana Silva; Pereira, H.; Yan, Leping; Gonçalves, Vera M.; Oliveira, A. L.; Oliveira, Joaquim M.; Reis, R. M.; Mendes, João EspregueiraMeniscus lesions are among the most common orthopaedic injuries which can ultimately lead to degeneration of the knee articular cartilage. The human meniscus has a limited healing potential, partly due to a poor vasculature, and thus meniscus regeneration using tissue engineering strategies has recently been investigated as a promising alternative to total/partial meniscectomy [1]. Advanced scaffolds for tissue...
In vitro and in vivo biological performance of modified gellan gum-based hydrog...
Correia, Joana Silva; Zavan, B.; Vindigni, V.; Oliveira, M. B.; Mano, J. F.; Pereira, H.; Oliveira, Joaquim M.; Mendes, João Espregueira; Abatangelo, G.Ionic- (iGG-MA) and photo-crosslinked (phGG-MA) methacrylated gellan gum hydrogels have been proposed as biomaterials for supporting nucleus pulposus (NP) regeneration and/or repair. In this study, the mechanical stability and biocompatibility of these hydrogels have been evaluated in vitro. Human intervertebral disc cells obtained from herniated patients were cultured within both hydrogels, for 1–21 days. Dyna...
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