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Characterization of 111In3+ complexes of DTPA amide derivatives: biodistributio...
Prata, M. I. M.; Santos, A. C.; Bligh, S. W. A.; Chowdhury, A. H. M. S.; Geraldes, C. F. G. C.; Lima, J. J. P. deA large series of structurally related diethylenetriaminepentaacetic acid amide derivatives with different structures and lipophilic properties were synthesized and radiolabeled with 111In3+. Two of the more hydrophobic compounds studied ([111In]L9 and [111In]L10) showed high affinity for human serum albumin (HSA). The biodistribution and clearance properties shown by all complexes upon injection in Wistar rats...
Data: 2000
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Origem: Estudo Geral - Universidade de Coimbra
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