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A comparative analysis of scaffold material modifications for load-bearing appl...
Chim, H.; Hutmacher, D. W.; Chou, A.; Oliveira, A. L.; Reis, R. L.; Lim, T. C.; Schantz, J. T.To facilitate optimal application of appropriate scaffold architectures for clinical trials, there is a need to compare different scaffold modifications under similar experimental conditions. In this study was assessed the effectiveness of poly-e-caprolactone (PCL) scaffolds fabricated by fused deposition modelling (FDM), with varying material modifications, for the purposes of bone tissue engineering. The inco...
Preliminary study on the adhesion and proliferation of human osteoblasts on sta...
Salgado, A. J.; Gomes, Manuela E.; Chou, A.; Coutinho, O. P.; Reis, R. L.; Hutmacher, D. W.Up to today, several techniques have been used to produce biodegradable porous scaffolds for tissue engineering. In this work, a new technique based on extrusion by using blowing agents in combination with a 50:50 (wt.%) blend of starch/cellulose acetate (SCA) was studied. The results show that by using this technique it was possible to obtain scaffolds with 70% of porosity and a fully interconnected network of...
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