The main purpose of this study was to construct reference standards for physical fitness (PF) values, and to graphically highlight differences between Vouzela children and adolescents’ PF levels with those from other national and international references samples. Sample comprised 1920 children and adolescents aged 7 to 17 years. PF was assessed by five tests: handgrip, standing jump, shuttle run, 50-yard dash a...
Human ERBB2 is a proto-oncogene that codes for the erbB-2 epithelial growth factor receptor. In human breast cancer (HBC), erbB-2 protein overexpression has been repeatedly correlated with poor prognosis. In more recent works, underexpression of this gene has been described in HBC. Moreover, it is also recognised that oncogenes that are commonly amplified or deleted encompass point mutations, and some of these ...
Cancer cell lines have been shown to be reliable tools in genetic studies of breast cancer, and the characterization of these lines indicates that they are good models for studying the biological mechanisms underlying this disease. Here, we describe the molecular cytogenetic/genetic characterization of two sister rat mammary tumor cell lines, HH-16 cl.2/1 and HH-16.cl.4, for the first time. Molecular cytogeneti...
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