In the search for new leishmanicidal agents, Thymus capitellatus Hoffmanns. & Link (familyLamiaceae) volatile extract and its major compounds, 1,8-cineole and borneol, were testedagainst Leishmania infantum, Leishmania tropica and Leishmania major. Plant volatile extract(essential oil) was analysed by GC and GC–MS and the activity of essential oil on Leishmaniapromastigotes viability was assessed using tetrazol...
In the search for new leishmanicidal agents, Thymus capitellatus Hoffmanns. & Link (family Lamiaceae) volatile extract and its major compounds, 1,8-cineole and borneol, were tested against Leishmania infantum, Leishmania tropica and Leishmania major. Plant volatile extract (essential oil) was analysed by GC and GC–MS and the activity of essential oil on Leishmania promastigotes viability was assessed using tetr...
Introdução e Objetivos: A desnervação simpática renal seletiva (DSRS) é um procedimento endovascular minimamente invasivo, seguro, recentemente desenvolvido para o tratamento da hipertensão resistente (HR). Até 6 ablações por radiofrequência (RF), com 2 minutos cada são aplicadas em ambas as artérias renais, estando associadas a dor abdominal visceral difusa, muito intensa1,2. Não foi encontrada literatura sobr...
Nuclear factor-kappaB is a key transcription factor activated by pro-inflammatory signals, like interleukin-1beta (IL-1), being required for the expression of many inflammatory and catabolic mediators, such as nitric oxide (NO), that play an important role in arthritic diseases. This work aimed at screening and identifying natural inhibitors of IL-induced NF-kappaB activation and NO production in human articula...
The chemical composition of the essential oils obtained by hydrodistillation from the aerial parts of Mentha cervinacollected during the flowering and vegetative phases of the plants were investigated by GC and GC-MS. Quantitative differences were observed in the compositions, particularly in the amounts of pulegone (12.9–79.6%) and isomenthone (8.7–77.0%). Antifungal activity of the oils was evaluated by minim...
O presente trabalho teve por objetivo a análise comparativa dos óleos voláteis de espécies da família Piperaceae. As espécies estudadas foram as seguintes: Piper aduncum, P. amalago, P. arboreum, P. cernuum, P. hispidum, P. regnelii, P. submarginalum, P. vicosanum e Pothomorphe umbellata. A análise dos óleos voláteis foi efetuada pela combinação de técnicas de Cromatografia de Fase Gasosa (CG) e de Cromatografi...
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