Encontrados 5 documentos, a visualizar página 1 de 1
Neuregulin attenuates pulmonary endothelial dysfunction in an experimental mode...
Adão, R.; Maia-Rocha, C.; Mendes-Ferreira, P.; Mendes, M.J.; Cerqueira, R.J.; Castro-Chaves , P.; De Keulenaer, G.W.; Leite-Moreira, A.F.[abstract] ; [resumo]
A neuregulina-1 atenua a disfunção endotelial na hipertensão arterial pulmonar
Mendes-Ferreira, P.; Adão, R.; Cerqueira, R.J.; Maia-Rocha, C.; Mendes, M.J.; Castro-Chaves, P.; De Keulenaer, G.W.; Leite-Moreira, A.F.[abstract] ; [resumo]
Negative inotropic effect of selective AT2 receptor stimulation and its modulat...
Castro-Chaves P; Soares S; Fontes-Carvalho R; Leite-Moreira AF
Inotropic and lusitropic effects of ghrelin and their modulation by the endocar...
Soares, JB; Rocha-Sousa, A; Castro-Chaves, P; Henriques-Coelho, T; Leite-Moreira, AFContractile effects of ghrelin (10(-9) to 10(-6) M) were tested in rat papillary muscles of normal (n = 50) and hypertrophic (n = 16) right ventricles (RV). RV hypertrophy was induced by pulmonary hypertension using monocrotaline. In normal muscles, ghrelin was added either alone (n = 9) or after pre-treatment with indomethacin (cycloxygenase inhibitor, 10(-5) M; n = 10), L-nitro-L-arginin (NO synthase inhibito...
Contractile effects of Ghrelin and expression of its receptor GHS-R1a in normal...
Soares, JB; Rocha-Sousa, A; Castro-Chaves, P; Henriques-Coelho, T; Roncon-Albuquerque R, Jr.; Leite-Moreira, AFINTRODUCTION: Ghrelin, isolated in 1999, is an endogenous ligand for the growth hormone secretagogue receptor (GHS-R1a). Recent studies suggest that it may influence the function of normal and failing hearts. Nonetheless, it has been difficult to differentiate its effects on the intrinsic properties of the myocardium from the secondary effects resulting from growth hormone release and vasomotor action. This stu...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||