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Drug-Induced Anaphylaxis Survey in Portuguese Allergy Departments
Faria, E; Rodrigues-Cernadas, J; Gaspar, A; Botelho, C; Castro, EBACKGROUND AND OBJECTIVE: Drug-induced anaphylaxis is an unpredictable and potentially fatal adverse drug reaction. The aim of this study was to identify the causes of drug-induced anaphylaxis in Portugal. METHODS: During a 4-year period a nationwide notification system for anaphylaxis was implemented, with voluntary reporting by allergists. Data on 313 patients with drug anaphylaxis were received and reviewed....
Age Influence on Functional Outcome of Patients With Sequelae of Traumatic Spin...
Santos, Joana Machado; Interna de Formação Específica de MFR do Hospital de Braga, PortugalObjectives: To evaluate the relationship between age and functional outcome in patients with sequelae of Traumatic Spinal Cord Injury (TSCI).Material and Methods: Retrospective study, with a 88 patients sample that were admitted as inpatients in Physical Medicine and Rehabilitation (PMR) Department of Hospital de Braga, between the years 2007 and 2011, with sequelae of TSCI. Clinical files were consulted and tw...
Drug-Induced Anaphylaxis Survey in Portuguese Allergy Departments
Faria, E; Rodrigues-Cernadas, J; Gaspar, A; Botelho, C; Castro, E; Morais-Almeida, MBACKGROUND AND OBJECTIVE: Drug-induced anaphylaxis is an unpredictable and potentially fatal adverse drug reaction. The aim of this study was to identify the causes of drug-induced anaphylaxis in Portugal. METHODS: During a 4-year period a nationwide notification system for anaphylaxis was implemented, with voluntary reporting by allergists. Data on 313 patients with drug anaphylaxis were received and reviewed....
Associação dos Fenótipos da Haptoglobina com os Lípidos e Apolipoproteínas Séri...
M. Guerra, A. J.; B. Castro, E. M.; Guerra, F. Carvalho; Rego, C.; Monteiro, C.; Prata, A.; Silva, D.; Bicho, M.; Santos, N. TeixeiraA aterosclerose e a hipertensão arterial iniciam-se precocemente na idade pediátrica, ainda que as expressões clínicas da doença cardio-cérebro-vascular se manifestem apenas na idade adulta. É objectivo primordial de numerosos estudos transversais e prospectivos a identificação dos principais factores risco, quer genéticos quer ambientais, relativamente ao processo aterosclerótico de modo a traçar estratégias d...
Impactação de prótese dentária no esófago torácico: tratamento cirúrgico. A pro...
Alexandrino, A; Fernandes, M; Ferreira, L; Tralhão, JG; Castro e Sousa, F
Study of hepatocellular function in the murine model following hepatic artery s...
Tralhão, JG; Abrantes, AM; Gonçalves, AC; Hoti, E; Laranjo, M; Martins, R; Oliveiros, B; Cardoso, D; Sarmento-Ribeiro, AB; Botelho, MFPURPOSE: To investigate the impact of selective hepatic artery clamping (SHAC) in hepatocellular function. METHODS: Three groups of Wistar male rats were subjected to SHAC ischemia period of 60min: Group A continuous SHAC were subjected to SHAC ischemia period of 60min, Group B intermittent SHAC of 30min with 5min of reperfusion and Group C intermittent SHAC of 15min with 5min of reperfusion. Animals without SH...
Bacterial protein azurin as a new candidate anticancer drug by decreasing cell ...
Abreu, Sofia de Almeida Santos de Castro eA azurina é uma proteína de 14 kDa produzida por Pseudomonas aeruginosa, com actividade citotóxica em linhas celulares cancerígenas humanas. A azurina entra preferencialmente em células cancerígenas, formando um complexo com a proteína supressora tumoral p53, estabilizando-a e induzindo a apoptose. A capacidade de migração e invasão deve-se, em parte, à regulação de proteínas de adesão celular, como a P-caderin...
Laser monotherapy in plantar fasciitis
Matos, Catarina; Médica Interna de Medicina Física e de Reabilitação do Centro Hospitalar de Lisboa Central, Hospital de São José, PortugalIntroduction: Plantar Fasciitis (PF) represents the most common cause of plantar heel pain. An initial conservative trial is recommended. Objectives: To characterize demographic and symptomatic factors, previous therapy, results with laser monotherapy. Material and Methods: Observational retrospective study (12 months period). The treatment consisted of infrared laser (AsGa 904nm; energy density 20J/cm2; peak p...
Monoterapia com Laser na Fasceíte Plantar
Matos, C; Castro e Cunha, A; Lorga, S; Cabral, ML; Oliveira, VIntrodução: A fasceíte plantar (FP) constitui a causa mais frequente de dor no retropé. Está recomendada uma prova terapêutica inicial conservadora. Objetivos: Caraterizar fatores demográficos e sintomáticos, terapêutica prévia e resultados de monoterapia com laser. Material e Métodos: Estudo observacional retrospetivo (12 meses). O tratamento aplicado foi laser infravermelho (AsGa 904nm; densidade de energia 2...
Synthesis and characterization of stable dicarboxylic pegylated magnetite nanop...
Gil, Sara; Castro, E.; Mano, J. F.The coating of implantable nano- or micro-objects with polyethylene glycol (PEG) enhances its biocompatibility and biodistribution. Herein, we describe a new protocol that enhances and maintains MNPs stability in biological media, simulating multiple conditions to which they would be subjected in the human body. Magnetite nanoparticles (MNPs) prepared via a facile way at room temperature by co-precipitation rea...
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