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Application of a high-throughput process analytical technology metabolomics pip...

Abstract Metabolomics aims at gathering the maximum amount of metabolic information for a total interpretation of biological systems. A process analytical technology pipeline, combining gas chromatography�mass spectrometry data preprocessing with multivariate analysis, was applied to a Port wine �forced ageing� process under different oxygen saturation regimes at 60 �C. It was found that extreme �forced ageing�...

Pheno-metabolomics characterization of a Saccharomyces cerevisiae strain collec...

Genotypic and pheno-metabolomic characterization of a Saccharomyces cerevisiae ...

The objective of the present work was to gain a deeper understanding of the phenotypic diversity of natural isolates of Saccharomyces cerevisiae, using high-throughput methods in combination with bioanalytical data. A S. cerevisiae strain collection was constituted comprising 187 strains from different geographical origins and technological uses. Some microsatellite alleles and phenotypes were identified as res...

Characterization of wine fermentations using fiber optic-mediated UV-VIS-SWNIR ...

Spectroscopy is widely used in biological sciences, being applied to liquids, pastes, powders, films, fibers, gases and surfaces. It makes possible to characterize proteins, peptides, lipids, membranes and carbohydrates in pharmaceuticals, foods, plants or animal tissues. It can also provide detailed information about the structure and mechanism of action of molecules. UV-VIS-SWNIR spectroscopy has not been use...

The genotypic and pheno-metabolomic landscape of a Saccharomyces cerevisiae str...

Yeast metabolic state identification by fiber optics spectroscopy

In this manuscript we explore the feasibility of using LWUV-VIS-SWNIR (340 - 1100 nm) spectroscopy to classify Saccharomyces cerevisiae colony structures in YP agar and YPD agar, under different growth conditions, such as: i) no alcohol; ii) 1 % (v/v) Ethanol; iii) 1 % (v/v) 1-Propanol; iv) 1 % (v/v) 1- butanol; v) 1 % (v/v) Isopropanol; vi) 1 % (v/v) (±)-1-Phenylethanol; vii) 1 % (v/v) Isoamyl alcohol; viii) 1...

The X-windows high-throughput mass spectroscopy pipeline

Late-life depression, heart failure and frontal white matter hyperintensity: a ...

The relevance of the relationship between cardiac disease and depressive symptoms is well established. White matter hyperintensity, a bright signal area in the brain on T2-weighted magnetic resonance imaging scans, has been separately associated with cardiovascular risk factors, cardiac disease and late-life depression. However, no study has directly investigated the association between heart failure, major dep...