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Analytical method for the determination of strychnine in tissues by gas chromat...
Marques, E. P.; Gil, F.; Proença, P.; Monsanto, P.; Oliveira, M. F.; Castanheira, A.; Vieira, D. N.This paper describes an analytical method for strychnine determination in biological samples by gas chromatography/mass spectrometry and their application in the investigation of two cases involving strychnine ingestion: A fatal case and a clinical one. The strychnine is isolated from biological samples using a liquid-liquid extraction procedure. The clean-up procedure is performed using an acid solution. Papav...
Oesophageal lichen planus
Souto, P; Sofia, C; Pina-Cabral, JE; Castanheira, A; Saraiva, S; Tellechea, O; Donato, A; Freitas, DLichen planus is a common skin and mucosal disease, with very rare symptomatic oesophageal involvement. We report a case of painful dysphagia due to oesophageal lichen planus in a 60-year-old woman who also had oral, cutaneous and genital lichen planus lesions. Steroid treatment produced considerable improvement of all lesions and a rapid symptomatic remission.
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