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Drug release assays from new chitosan/pHEMA membranes obtained by gamma irradia...
Casimiro, M. H.; Gil, M. H.; Leal, J. P.With the purpose of obtaining a biocompatible and microbiologically safe matrix that simultaneously could be used as wound dressing material and as a controlled drug release system, membranes with different thickness and different contents in chitosan and hydroxyethyl methacrylate (HEMA) have been prepared by [gamma] irradiation from a 60Co source. Antibiotic release experiments were performed before or after i...
Characterisation of gamma irradiated chitosan/pHEMA membranes for biomedical pu...
Casimiro, M. H.; Leal, J. P.; Gil, M. H.As a polysaccharide of natural origin, chitosan has the inherent properties of being biocompatible, biodegradable, and non-toxic. These properties make chitosan an ideal candidate for based backbone in copolymeric matrices for use in biomedical applications. Poly(hydroxyethyl methacrylate) is a synthetic hydrogel which possesses a high mechanical strength. The conjunction of these two components results in a ne...
Study on chemical, UV and gamma radiation-induced grafting of 2-hydroxyethyl me...
Casimiro, M. H.; Botelho, M. L.; Leal, J. P.; Gil, M. H.In the present study, 2-hydroxyethyl methacrylate has been grafted onto chitosan by using either chemical initiation, or photo-induction or gamma radiation-induced polymerisation, all under heterogeneous conditions. The evidence of grafting was provided by Fourier transform infrared spectroscopy and thermal analysis. ; http://www.sciencedirect.com/science/article/B6TVT-4CJV8FD-H/1/40853b848ce3f663d431d10fb6e...
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