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The role of glycoprotein 130 family of cytokines in fetal rat lung development
Nogueira-Silva, C; Piairo, P; Carvalho-Dias, E; Veiga, C; Moura, RS; Correia-Pinto, JThe glycoprotein 130 (gp130) dependent family of cytokines comprises interleukin-6 (IL-6), IL-11, leukemia inhibitory factor (LIF), cardiotrophin-like cytokine (CLC), ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1) and oncostatin M (OSM). These cytokines share the membrane gp130 as a common signal transducer. Recently, it was demonstrated that IL-6 promotes, whereas LIF inhibits fetal lung branching....
Three-dimensional vs standard laparoscopy: comparative assessment using a valid...
Cicione, A; Autorino, R; Breda, A; De Sio, M; Damiano, R; Fusco, F; Greco, F; Carvalho-Dias, E; Mota, P; Nogueira, C; Pinho, P; Mirone, VOBJECTIVE: To compare the last generation of 3-dimensional imaging (3D) vs standard 2-dimensional imaging (2D) laparoscopy. MATERIALS AND METHODS: A prospective observational study was conducted during the 4th Minimally Invasive Urological Surgical Week Course held in Braga (Portugal) in April 2013. The course participants and faculty were asked to perform standardized tasks in the dry laboratory setting and ra...
The role of glycoprotein 130 family of cytokines in fetal rat lung development
Nogueira-Silva, C; Piairo, P; Carvalho-Dias, E; Veiga, C; Moura, RS; Correia-Pinto, JThe glycoprotein 130 (gp130) dependent family of cytokines comprises interleukin-6 (IL-6), IL-11, leukemia inhibitory factor (LIF), cardiotrophin-like cytokine (CLC), ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1) and oncostatin M (OSM). These cytokines share the membrane gp130 as a common signal transducer. Recently, it was demonstrated that IL-6 promotes, whereas LIF inhibits fetal lung branching....
Three-dimensional vs standard laparoscopy: comparative assessment using a valid...
Cicione, A; Autorino, R; Breda, A; De Sio, M; Damiano, R; Fusco, F; Greco, F; Carvalho-Dias, E; Mota, P; Nogueira, C; Pinho, P; Mirone, VOBJECTIVE: To compare the last generation of 3-dimensional imaging (3D) vs standard 2-dimensional imaging (2D) laparoscopy. MATERIALS AND METHODS: A prospective observational study was conducted during the 4th Minimally Invasive Urological Surgical Week Course held in Braga (Portugal) in April 2013. The course participants and faculty were asked to perform standardized tasks in the dry laboratory setting and ra...
Leukemia inhibitory factor in rat fetal lung development: expression and functi...
Nogueira-Silva, C; Piairo, P; Carvalho-Dias, E; Peixoto, FO; Moura, RS; Correia-Pinto, JBACKGROUND: Leukemia inhibitory factor (LIF) and interleukin-6 (IL-6) are members of the family of the glycoprotein 130 (gp130)-type cytokines. These cytokines share gp130 as a common signal transducer, which explains why they show some functional redundancy. Recently, it was demonstrated that IL-6 promotes fetal lung branching. Additionally, LIF has been implicated in developmental processes of some branching ...
Leukemia inhibitory factor in rat fetal lung development: expression and functi...
Nogueira-Silva, C; Piairo, P; Carvalho-Dias, E; Peixoto, FO; Moura, RS; Correia-Pinto, JBACKGROUND: Leukemia inhibitory factor (LIF) and interleukin-6 (IL-6) are members of the family of the glycoprotein 130 (gp130)-type cytokines. These cytokines share gp130 as a common signal transducer, which explains why they show some functional redundancy. Recently, it was demonstrated that IL-6 promotes fetal lung branching. Additionally, LIF has been implicated in developmental processes of some branching ...
Local Fetal Lung Renin-Angiotensin System as a Target to Treat Congenital Diaph...
Nogueira-Silva, C; Carvalho-Dias, E; Piairo, P; Nunes, S; Baptista, MJ; Moura, RS; Correia-Pinto, JAntenatal stimulation of lung growth is a reasonable approach to treat congenital diaphragmatic hernia (CDH), a disease characterized by pulmonary hypoplasia and hypertension. Several evidences from the literature demonstrated a possible involvement of renin-angiotensin system (RAS) during fetal lung development. Thus, the expression pattern of renin, angiotensin-converting enzyme, angiotensinogen, type 1 (AT(1...
Local Fetal Lung Renin-Angiotensin System as a Target to Treat Congenital Diaph...
Nogueira-Silva, C; Carvalho-Dias, E; Piairo, P; Nunes, S; Baptista, MJ; Moura, RS; Correia-Pinto, JAntenatal stimulation of lung growth is a reasonable approach to treat congenital diaphragmatic hernia (CDH), a disease characterized by pulmonary hypoplasia and hypertension. Several evidences from the literature demonstrated a possible involvement of renin-angiotensin system (RAS) during fetal lung development. Thus, the expression pattern of renin, angiotensin-converting enzyme, angiotensinogen, type 1 (AT(1...
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