Encontrados 7 documentos, a visualizar página 1 de 1
Common genetic polymorphisms in the ABCB1 gene are associated with risk of majo...
Santos, Marlene; Carvalho, Serafim; Lima, Luís; Nogueira, Augusto; Assis, Joana; Mota-Pereira, Jorge; Pimentel, Paulo; Maia, Dulce; Correia, DianaMajor depressive disorder (MDD) is a highly prevalent disorder, which has been associated with an abnormal response of the hypothalamus–pituitary–adrenal (HPA) axis. Reports have argued that an abnormal HPA axis response can be due to an altered P-Glycoprotein (P-GP) function. This argument suggests that genetic polymorphisms in ABCB1 may have an effect on the HPA axis activity; however, it is still not clear i...
Internato de Psiquiatria Rumo a Um Futuro Global: A Perspectiva dos Internos em...
Pinto da Costa, Mariana; Psychiatry Department. Hospital de Magalhães Lemos. Porto. Portugal.Introduction: Psychiatry is influenced by society changes, so it should be permanently updating itself, foreseeing future behaviours and pathologies. This study aims to describe psychiatry trainee’s opinion in Portugal concerning their training and the modifications they would want to witness in the near future.Material and Methods: A structured questionnaire of 26 questions was developed by the Portuguese Asso...
Moderate exercise as an adjuvant therapy for treatment-resistant major depressi...
Mota-Pereira, Jorge; Silvério, Jorge Manuel Amaral; Fonte, Daniela; Carvalho, Serafim; Ramos, Joaquim; Ribeiro, José CarlosAlthough several international guidelines recommend exercise to reduce symptoms of Major Depressive Disorder (MDD), data concerning the long-term effects of exercise in depression are still extremely scarce. Therefore, and in order to assess these long-term effects, we have evaluated treatment-resistant MDD patients previously enrolled in a moderate intensity 12 week exercise program at 3 and 6 months after...
Exercise intervention in treatment-resistant major depressive disorder : benefi...
Mota-Pereira, Jorge; Ribeiro, José Carlos; Fonte, Daniela; Carvalho, Serafim; Ramos, Joaquim; Silvério, Jorge Manuel AmaralAlthough there are several reports on the benefits of exercise on Major Depressive Disorder, none has monitored these exercise programs with accelerometers. We have conducted a 12 week home based moderate intensity exercise program in 33 treatmentresistant Major Depressive Disorder patients and, based on accelerometer data, determined compliance, exercise patterns and relationship between time spent in MVPA...
Variáveis Sócio-Cognitivas como Preditores da Resposta ao Tratamento Farmacológ...
Carvalho, Serafim Armindo DiasIntrodução: resistência, remissão tardia, remissão incompleta com sintomas residuais e recaída ou recorrência são frequentes durante o tratamento farmacológico da depressão. O resultado do tratamento depende do intervalo temporal considerado e dos critérios utilizados como referência. Por outro lado, os estudos têm sido inconclusivos em relação à maior parte dos preditores e só em relação a um pequeno número de...
Evolutionary medicine: the future looking at the past.
Carvalho, Serafim; Rosado, MargaridaEvolutionary medicine is an emergent basic science that offers new and varied perspectives to the comprehension of the human health and disease, considering them as a result of a gap between our modern lives and the environment where human beings evolve. This work's goals are to understand the importance of the evolutionary theories on concepts of health and disease, providing a new insight on medicine investig...
Perturbação de pânico : Suas apresentações clínicas
Carvalho, Serafim Armindo Dias deObjectivos- As características clínicas dos doentes com perturbação de pânico nunca foram exaustivamente estudadas entre nós. Por outro lado a perturbação de pânico pode ser uma realidade clínica mais heterogénea do que geralmente é suposto. Partimos para esta investigação com o propósito, não só de avaliar dados de uma amostra do nosso meio sociocultural, como demonstrar que alguns subtipos sintomáticos da per...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||