Encontrados 61 documentos, a visualizar página 1 de 7
Gentrification, residential ethnicization and the social production of fragment...
Malheiros, Jorge; Carvalho, Rui; Mendes, LuisSimultaneous trends for ethnicization and gentrification are contributing to the fragmentation of contemporary urban spaces. This is characterised by the emergence of new social and urban units that break the homogeneity of the modern city and lead to the development of new networks, territorially discontinuous, less neighbourhood centred and with a limited intersection. With Mouraria (Lisbon, Portugal) and San...
Portugal, the Mediterranean and the Atlantic. Geographical study
Carvalho, Rui(sem entrada)
Insights into the Synthesis of Steroidal A-Ring Olefins
Varela, Carla M.; Roleira, Fernanda M. F.; Costa, Saul C. P.; Tinto, Alexandra S. C. T.; Martins, Ana I. O. S.; Carvalho, Rui A.; Teixeira, Natércia A.one (5), from the D1-3-keto enone, (5a,17b)-3-oxo-5-androst-1-en-17-yl acetate (1), through a strategy involving the reaction of D1-3-hydroxy allylic alcohol, 3b-hydroxy-5a-androst-1-en-17b-yl acetate (2), with SOCl2 , was revisited in order to prepare and biologically evaluate 5 as aromatase inhibitor for breast cancer treatment. Surprisingly, the followed strategy also afforded the isomeric D2-olefin 6 as a b...
Revenue forecast errors in the European Union
Afonso, António; Carvalho, RuiIn this paper we assess the determinants of revenue forecast errors for the EU-15 between 1999 and 2012, based on the forecasts published bi-annually by the European Commission. Our results show that personal income rate changes increase the revenue forecast errors: for forecasts made in t for t, increases in the corporate tax rate implies a decrease in the revenue forecast errors, in t+1 and t+2. Moreover, an ...
Síndrome de Wolfram. A Propósito de Um Caso Clínico
Figueiredo, Ana Cristina; Pinto, Eduarda; Frutuoso, Simão; Dores, Jorge; Carvalho, Rui; Alves, ValterA síndrome de Wolfram, inicialmente descrita em 1938, caracteriza-se pela associação de Diabetes Mellitus, atrofia óptica e de forma mais inconstante surdez, Diabetes Insípida, alterações urinárias e neurológicas. Esta síndrome, frequentemente familiar, tem uma transmissão autossómica recessiva, tendo sido descrita recentemente uma ligação a marcadores no braço curto do cromossoma 4.Descreve-se o caso de uma me...
Doxorubicin-Induced Cardiotoxicity: From Bioenergetic Failure and Cell Death to...
Carvalho, Filipa S.; Burgeiro, Ana; Garcia, Rita; Moreno, Antonio J.; Carvalho, Rui A.; Oliveira, Paulo J.Doxorubicin (DOX) is an anticancer anthracycline that presents a dose-dependent and cumulative cardiotoxicity as one of the most serious side effects. Several hypotheses have been advanced to explain DOX cardiac side effects, which culminate in the development of life-threatening cardiomyopathy. One of the most studied mechanisms involves the activation of DOX molecule into a more reactive semiquinone by mitoch...
Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Mai...
Sandro, L. Pereira; Grãos, Mário; Rodrigues, Ana Sofia; Anjo, Sandra I.; Carvalho, Rui A.; Oliveira, Paulo J.; Arenas, Ernest; Ramalho-Santos, JoãoThe mitochondrion is emerging as a key organelle in stem cell biology, acting as a regulator of stem cell pluripotency and differentiation. In this study we sought to understand the effect of mitochondrial complex III inhibition during neuronal differentiation of mouse embryonic stem cells. When exposed to antimycin A, a specific complex III inhibitor, embryonic stem cells failed to differentiate into dopaminer...
Atividades colaborativas em processos suportados por BPMS
Carvalho, Rui José SilvaDissertação de mestrado em Engenharia e Gestão de Sistemas de Informação ; Atualmente, as organizações cada vez mais optam por adotar modelos de gestão baseados em processos, tornando-se mais competitivas, minorando os seus gastos e alcançando maior produtividade. Tentando contribuir para o alinhamento dos processos de negócio com a estratégia das organizações, surgiu o Business Process Management como a abord...
Revenue forecast errors in the European Union
Carvalho, Rui Miguel da CostaMestrado em Economia Monetária e Financeira ; The recent years had brought significant uncertainty to macroeconomic forecasts made not only by specialized international institutions but also by central governments. This dissertation assesses the determinants of revenue forecast errors for the EU-15 between 1999 and 2012, based on the forecasts published bi-annually by the European Commission. A particular impo...
Integração das actividades logísticas e vantagens competitivas nas farmácias co...
Carvalho, Rui Alexandre Pincante deSeja qual for o seu sector, a logística nasce dentro das organizações, não estando as actividades das farmácias comunitárias obstante a esta lógica. Esta define-se como um processo que dirige estrategicamente as movimentações dos materiais essenciais às actividades da organização. Neste sentido, não podemos ignorar a necessidade de construir estratégias inerentes às actividades logísticas, para que seja possíve...
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