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Exploring a link between mycobacteria structure and virulence
Silva, Carla; Perdigao, Joao; Alverca, Elsa; Matos, António Pedro Alves; Carvalho, Patrícia A; Portugal, Isabel; Jordao, LuisaTuberculosis (TB) is a major health problem. The emergence of multidrug resistant (MDR)Mycobacterium tuberculosis (Mtb) isolates confounds treatment strategies. In Portugal, cases of MDR-TB are reported annually with increased incidence noted in Lisbon. The majority of these MDR-TB cases are due to closely-related mycobacteria known collectively as Lisboa family and Q1 cluster. The genetic determinants linked t...
Morphologic characterization of Mycobacterium tuberculosis circulating strains ...
Silva, Carla; Alverca, Elsa; Matos, António Pedro; Carvalho, Patricia A; Portugal, Isabel; Jordao, LuisaAbstrat publicado em: http://metallica.civil.ist.utl.pt/~patricia/SPMicros2012/book.pdf ; Tuberculosis (TB) is one of the major causes of mortality and morbidity worldwide accounting for 3.1 million deaths per year. This disease, caused by M. tuberculosis (Mtb) made a deadly, during the 1990’s, triggered mainly by the emergence of acquired immunodeficiency syndrome (AIDS). More recently, the emergence of multi...
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