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Dengue virus capsid protein binding to hepatic lipid droplets (LD) is potassium...
Carvalho, Filomena A.; Carneiro, Fabiana A.; Martins, Ivo C.; Assunção-Miranda, Iranaia; Faustino, André F.; Pereira, Renata M.; Bozza, Patricia T.Copyright © 2012, American Society for Microbiology. All Rights Reserved. ; Dengue virus (DENV) affects millions of people, causing more than 20,000 deaths annually. No effective treatment for the disease caused by DENV infection is currently available, partially due to the lack of knowledge on the basic aspects of the viral life cycle, including the molecular basis of the interaction between viral components ...
Variations on fibrinogen-erythrocyte interactions during cell aging
Carvalho, Filomena A.; Oliveira, Sofia de; Freitas, Teresa; Gonçalves, Sónia; Santos, Nuno C.© 2011 Carvalho et al ; Erythrocyte hyperaggregation, a cardiovascular risk factor, is considered to be caused by an increase in plasma adhesion proteins, particularly fibrinogen. We have recently reported a specific binding between fibrinogen and an erythrocyte integrin receptor with a β3 or β3-like subunit. In this study we evaluate the influence of erythrocyte aging on the fibrinogen binding. By atomic forc...
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