Encontrados 13 documentos, a visualizar página 1 de 2
Diabetes Mellitus and its Influence on the Success of Endodontic Treatment: A R...
Ferreira, Manuel Marques; Faculdade de Medicina Dentária. Universidade de Coimbra. Coimbra. Portugal.Introduction: Diabetes mellitus is an endocrine disease in which are involved the hormones produced by the islets of Langerhans. The diabetes mellitus can affect various functions of the immune system of the individual, predisposing them to chronic inflammation, progressive degradation of tissues and decreased tissue repair. The changes caused by this disease at the level of the oral cavity can highlight xerost...
Relation between Metformin Treatment and the Development of Hyperlactacidemia a...
Guelho, Daniela; Serviço de Endocrinologia, Diabetes e Metabolismo. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal.Introduction: In type 2 diabetic patients treated with metformin the development of hyperlactacidemia or even lactic acidosis seems to result from an acute precipitating event. This study aims to assess the prevalence and relative risk of hyperlactacidemia in diabetic patients admitted in the Emergency Room, the predictive factors for high lactate concentration and the influence of hyperlactacidemia in patients...
Thyroid Carcinoma in Children and Young Adults: Retrospective Review of 19 Cases
Saraiva, Joana; Departamento de Endocrinologia. Centro Hospitalar e Universitário de Coimbra. Coimbra. Portugal.Introduction: Thyroid carcinoma is rare in children and young adults. Most of management guidelines are based in data from adult population. Several controversies remain regarding the aggressiveness of clinical presentation and therapeutic approach.Objective: To evaluate all differentiated thyroid carcinoma patients with less than 20 years-old at presentation reflecting the experience of our unit in relation to...
Função Gonadal na Síndrome de Turner
Alves, Márcia; Serviço de Endocrinologia, Diabetes e Metabolismo. Centro Hospitalar e Universitário de Coimbra, EPE. Coimbra. Portugal.Introdução: A síndrome de Turner caracteriza-se pela ausência, parcial ou total, de um cromossoma X no sexo feminino, sendo uma das cromossomopatias mais frequentes. O diagnóstico é realizado através do cariótipo e as suas manifestações incluem o hipogonadismo primário, antes ou após a puberdade (disgenesia gonadal). O grau de disfunção e a extensão dos defeitos gonadais são variáveis.Objectivos: Pretendeu-se a...
Iodo e Tiróide: O que o Clínico Deve Saber
Santana Lopes, Maria; Jácome de Castro, João; Marcelino, Mafalda; Oliveira, Maria João; Carrilho, Francisco; Limbert, EdwardA Organização Mundial de Saúde considera a carência de iodo como a principal causa mundial evitável de doenças mentais e do desenvolvimento, estimando que cerca de 13% da população mundial esteja afectada por doenças causadas pela falta de iodo. O iodo é um oligoelemento necessário na síntese de hormonas tiroideias que, uma vez que não pode ser formado pelo organismo, tem de ser ingerido regularmente com a alim...
Iodine Intake in Portuguese School Children
Limbert, Edward; Prazeres, Susana; São Pedro, Márcia; Madureira, Deolinda; Miranda, Ana; Ribeiro, Manuel; Carrilho, Francisco; Jácome de Castro, JObjective: The aim of the present study was to evaluate iodine intake in portuguese school children in order to inform health authorities of eventual measures to be implemented. Introduction: Iodine is the key element for thyroid hormone synthesis and its deficiency even mild, as found in other European countries, may have deleterious effects in pregnancy resulting in cognitive problems of offsprings. In Portug...
Late onset congenital adrenal hyperplasia due to 21-hydroxylase deficiency: rev...
Vieira, Alexandra; Paiva, Sandra; Baptista, Carla; Ruas, Luísa; Silva, Júlia; Gonçalves, João; Carrilho, Francisco; Carvalheiro, ManuelaThe deficiency of the enzyme 21-hydroxylase (21-HO) is responsible for about 90% to 95% of all cases of congenital adrenal hyperplasia (HCSR). This disorder is one of the most frequent hereditary illnesses of autosomal recessive trait. The illness can be presented in two clinical forms: 1 - classic, subdivided in saltwasting form and simple virilizing form; 2 - nonclassic or late-onset. The severity of the illn...
Lack of association of vitamin D receptor gene polymorphisms with susceptibilit...
Lemos, Manuel C.; Fagulha, Ana; Coutinho, Eduarda; Gomes, Leonor; Bastos, Margarida; Barros, Luisa; Carrilho, Francisco; Geraldes, ElizabeteThe vitamin D receptor (VDR) gene is a candidate gene for susceptibility to autoimmune disorders. Association studies of VDR polymorphisms and risk of type 1 diabetes often produced conflicting results in different ethnic backgrounds. The aim of this study was to test for association between common VDR polymorphisms and the genetic susceptibility to type 1 diabetes in the Portuguese population. We genotyped 207...
Friedreich ataxia and diabetes mellitus--family study.
Melo, Miguel; Serviço de Endocrinologia, Diabetes e Metabolismo, Hospitais da Universidade de Coimbra, Coimbra.; Fagulha, Ana; Barros, LuisaFriedreich's ataxia (FA) is one of the genetic syndromes sometimes associated with diabetes and the most common hereditary ataxia. It is a autosomal recessive neurodegenerative disease, caused by a mutation in the FRDA gene, which originates decreased expression of frataxin, a mitochondrial protein involved in iron metabolism. The disorder is usually manifest in childhood and is characterised by ataxia, dysarth...
Diagnosis and Treatment of Solitary thyroid nodule – Study and Evaluation in Po...
Vilar, Helena; Sociedade Portuguesa de Endocrinologia, Diabetes e Metabolismo.; Carrilho, Francisco; Borges, Fátima; Limbert, EdwardIntroduction – The best diagnostic and treatment strategy for an approach to the nodular thyroid disease continues to be a controversial issue. Objectives – The aim of this study was to characterise medical practice in the diagnosis and treatment of nodular thyroid disease by endocrinologists and surgeons in Portugal in 2002. Methods – A questionnaire based on that used by the European Thyroid Association and t...
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