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Thyroid carcinoma in children and young adults: retrospective review of 19 cases
Saraiva, J; Ribeiro, C; Melo, M; Costa, G; Carrilho, FIntroduction: Thyroid carcinoma is rare in children and young adults. Most of management guidelines are based in data from adult population. Several controversies remain regarding the aggressiveness of clinical presentation and therapeutic approach. Objective: To evaluate all differentiated thyroid carcinoma patients with less than 20 years-old at presentation reflecting the experience of our unit in relation t...
The ALERT-ES Project: an Earthquake Early Warning System for S. Iberia
Buforn, E.; Carranza, M.; Udías, A.; Goula, X.; Colom, Y.; Roca, A.; Zollo, A.; Lozano, L.; Pro, C.; Carrilho, F.; Hanka, W.; Madariaga, R.The main goal of the ALERT-ES project (“Sistema de Alerta Sísmica Temprana: Aplicación al Sur de España”) is to study the feasibility of an Earthquake Early Warning System (EEWS) for SW Iberian Peninsula applied to the potentially damaging earthquakes that occur in the region of Cape S. Vicente-Gulf of Cadiz. This area is characterized by the occurrence of large earthquakes with damage in SW Iberia, such as tho...
Hiperplasia Congénita da Suprarrenal de Expressão Tardia por Deficiência de 21-...
Vieira, A; Paiva, S; Baptista, C; Ruas, L; Silva, J; Gonçalves, J; Carrilho, F; Carvalheiro, MThe deficiency of the enzyme 21-hydroxylase (21-HO) is responsible for about 90% to 95% of all cases of congenital adrenal hyperplasia (HCSR). This disorder is one of the most frequent hereditary illnesses of autosomal recessive trait. The illness can be presented in two clinical forms: 1 - classic, subdivided in saltwasting form and simple virilizing form; 2 - nonclassic or late-onset. The severity of the illn...
The ALERT-ES Project for earthquakes in Cape San Vicente region
Buforn, E.; Mattesini, M.; Martín Dávila, J.; Goula, X.; Colom, Y.; Zollo, Z.; Udías, A.; Pazos, A.; Roca, A.; Lozano, L.; Carrilho, F.; Hanka, W.The main goal of the ALERT-ES project ("Sistema de Alerta Sismica Temprana: Aplicacion al Sur de España" ) is to study the feasibility of an Earthquake Early Warning System (EEWS) for the potentially damaging earthquakes that occur in the zone Cape S. Vicente-Gulf of Cadiz (S. Spain). This area is characterized by the occurrence of large and damaging earthquakes such as the 1755 Lisbon (Imax=X) or 1969 S. Vicen...
Imaging 3D seismic velocity along the seismogenic zone of Algarve region (south...
Rocha, J; Bezzeghoud, M; Caldeira, B; Dias, N; Borges, JF; Dorbath, L; Carrilho, FThe present seismic tomographic study is focused around Algarve region, in South of Portugal. To locate the seismic events and find the local velocity structure of epicentral area, the P and S arrival times at 38 stations are used. The data used in this study were obtained during the Algarve campaign which worked from January/2006 to July/2007. The preliminary estimate of origin times and hypocentral coordinate...
Does hepatocellular carcinoma in non-alcoholic steatohepatitis exist in cirrhot...
Chagas,A.L.; Kikuchi,L.O.O.; Oliveira,C.P.M.S.; Vezozzo,D.C.P.; Mello,E.S.; Oliveira,A.C.; Cella,L.C.; Herman,P.; Bachella,T.; Caldwell,S.H.Non-alcoholic steatohepatitis (NASH) has been associated with hepatocellular carcinoma (HCC) often arising in histologically advanced disease when steatohepatitis is not active (cryptogenic cirrhosis). Our objective was to characterize patients with HCC and active, histologically defined steatohepatitis. Among 394 patients with HCC detected by ultrasound imaging over 8 years and staged by the Barcelona Clinic L...
The CTLA4 +49 A/G polymorphism is not associated with susceptibility to type 1 ...
Lemos, MC; Coutinho, E; Gomes, L; Bastos, M; Fagulha, A; Barros, L; Carrilho, F; Geraldes, E; Regateiro, FJ; Carvalheiro, MCTLA4 genetic polymorphisms have been associated with type 1 diabetes. We genotyped 207 patients and 249 controls for the most frequently investigated polymorphism of the CTLA4 gene (+49A/G (rs231775)). No significant differences were observed, suggesting that this polymorphism is not strongly associated with type 1 diabetes in the Portuguese population.
Low occurrence of occult hepatitis B virus infection and high frequency of hepa...
Alencar,R.S.M.; Gomes,M.M.S.; Sitnik,R.; Pinho,J.R.R.; Malta,F.M.; Mello,I.M.V.G.C.; Mello,E.S.; Bacchella,T.; Machado,M.C.C.; Alves,V.A.F.Occult hepatitis B virus (HBV) infection has been reported among patients with hepatitis C virus (HCV) infection and hepatocellular carcinoma (HCC). Our aim was to evaluate the presence of occult HBV infection in patients with HCV-related liver cirrhosis (LC) with or without HCC in São Paulo, Brazil. Serum and liver tissue samples from 50 hepatitis B surface antigen-negative patients with HCV-related LC who und...
Lack of association of vitamin D receptor gene polymorphisms with susceptibilit...
Lemos, MC; Fagulha, A; Coutinho, E; Gomes, L; Bastos, M; Barros, L; Carrilho, F; Geraldes, E; Regateiro, FJ; Carvalheiro, MThe vitamin D receptor (VDR) gene is a candidate gene for susceptibility to autoimmune disorders. Association studies of VDR polymorphisms and risk of type 1 diabetes often produced conflicting results in different ethnic backgrounds. The aim of this study was to test for association between common VDR polymorphisms and the genetic susceptibility to type 1 diabetes in the Portuguese population. We genotyped 207...
Improving the seismic hazard evaluation of the Lisbon and Lower Tagus Valley area
Carvalho, João P. F.; Pinto, Carlos C.; Costa, M.; Heleno, S.; Silva, M.; Rabeh, Taha; Cooksley, G.; Carrilho, F.The Lisbon and surrounding area of the Lower Tagus Valley has experienced in the past the effects of several moderate sized earthquakes that caused significant damage and destruction. They have been attributed to local sources, though in some cases the source remains to be located. The lack of outcrops in the flat lying Quaternary terrains, the low slip-rates of the area in connection with sedimentation and ero...
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