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Effect of algae and plant lectins against bacterial biofilm formation

Vasconcelos, Mayron Alves; Arruda, Francisco Vassiliepe Sousa; Carneiro, Victor Alves; Nascimento, Kyria Santiago; Cavada, Benildo Sousa


Prophylactic outcomes of casbane diterpene in Candida albicans and Candida glab...

Vasconcelos, Mayron Alves; Santos, Hélcio Silva dos; Bandeira, Paulo Nogueira; Albuquerque, Maria Rose Jane Ribeiro; Carneiro, Victor Alves

Biofilms are surface associated communities of microorganisms embedded within a self-produced extracellular matrix and adhered on inert and biotic surfaces. These biological consortia are considered the most prevalent growth form of microorganisms. Biofilm formation is a potent virulence factor for a number of Candida species, as it confers significant tolerance to antimicrobial therapy, primarily by limiting t...


Casbane diterpene as a promising natural antimicrobial agent against biofilm-as...

Carneiro, Victor Alves; Santos, Hélcio Silva dos; Arruda, Francisco Vassiliepe Sousa; Bandeira, Paulo Nogueira; Albuquerque, Maria Rose Jane Ribeiro

Croton nepetaefolius is a native plant from northeastern Brazil that belongs to the Euphorbiaceae family. The biological action of this plant has been extensively explored, being the secondary metabolites responsible for its properties alkaloids, diterpenes, and triterpenes. This study aimed to evaluate the ability of casbane diterpene (CD), isolated from the ethanolic extract of C. nepetaefolius, to inhibit mi...


Evaluation of leguminous lectins activities against bacterial biofilm formation

Carneiro, Victor Alves; Cavalcante, Theodora Thays Arruda; Teixeira, Edson Holanda; Cavada, Benildo Sousa; Oliveira, Rosário; Henriques, Mariana

Biofilms are composed by microbial cells that are irreversibly associated with a surface and enclosed in a matrix of polymeric material. Lectins are sugar binding proteins of non immune origin that agglutinate cells and ⁄ or precipitate glycoconjugate molecules. Due to their capacity to bind and recognize specific carbohydrates, lectins can be a potent tool in biofilm studies. The search for potential phytochem...


Casbane diterpene as novel and natural antimicrobial agent against biofilm infe...

Carneiro, Victor Alves; Teixeira, Edson Holanda; Santos, Hélcio Silva dos; Pereira, M. O.; Henriques, Mariana; Lemos, Telma

Croton nepetaefolius is a plant native from northeastern Brazil and belongs to Euphorbiaceae family. The essential oil of this plant is widely used in folk medicine from the treatment of gastrointestinal disorders to the use as an antiseptic agent, with an antifungal action scientifically proven. The action of this plant has been extensively explored by the scientific community, being the secondary metabolites,...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia