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Dor Abdominal Recorrente e Infecção por Helicobacter pylori: PRIMUM NON NOCCERE

Costeira, M. J.; Soares, M. I.; Aguiar, A.; Rodrigues, F. C.; Carneiro, F.; Soares, J.; Sousa, J. C.; Silva, C.; Dias, J. Amil

A relação entre Dor Abdominal Recorrente (DAR) na criança e a infecção por Helicobacter pylori (Hp) tem sido longamente debatida, mantendo-se ainda um assunto polémico.No sentido de investigar este problema avaliaram-se 35 crianças com DAR da Consulta Externa de Gastroenterologia Pediátrica do Hospital de S. João.Métodos: Os doentes incluídos no estudo efectuaram investigação clínica e analítica adequada a cada...

Data: 2014   |   Origem: Acta Pediátrica Portuguesa

Validation of a PNA-FISH method for the detection of Helicobacter pylori

Cerqueira, L.; Fernandes, RM.; Ferreira, RM.; Oleastro, M.; Carneiro, F.; Brandão, C.; Pimentel-Nunes, P.; Dinis-Ribeiro, M.; Figueiredo, C.

Here, we evaluated a previously established peptide nucleic acid-fluorescence in situ hybridization (PNA-FISH) method as a new diagnostic test for Helicobacter pylori clarithromycin resistance detection in paraffin-embedded gastric biopsy specimens. Both a retrospective study and a prospective cohort study were conducted to evaluate the specificity and sensitivity of a PNA-FISH method to determine H. pylori cla...


A high-accuracy trajectory following controller for pneumatic devices

J. Falcão Carneiro; F. Gomes de Almeida

The use of pneumatic devices is widespread among different industrial fields, in tasks like handling or assembly. Pneumatic systems are low-cost, reliable, and compact solutions. However, its use is typically restricted to simple tasks due to the poor performance achieved in applications where accurate motion control is required. This paper presents a novel nonlinear controller, using neural network-based model...


Application of fluorescence in situ hybridisation using peptide nucleic acid pr...

Cerqueira, L.; Fernandes, R. M.; Ferreira, Rui M.; Carneiro, F.; Ribeiro, M. Dinis; Figueiredo, C.; Azevedo, N. F.; Keevil, C. W.; Vieira, M. J.

Microorganisms are responsible for several infectious diseases that can cause severe problems to patients and their treatment success is seriously correlated with the fast detection of the infectious agent. Some of the standard methods used, such as culturing methods are fastidious and time-consuming and do not give any information about the antibiotic resistance profile. Therefore, molecular methods have been ...


Helicobacter pylori colonization of the adenotonsillar tissue: fact or fiction?

Vilarinho, S; Guimarães, NM; Ferreira, RM; Gomes, B; Wen, XG; Vieira, MJ; Carneiro, F; Godinho, T; Figueiredo, C

OBJECTIVE: The transmission of the gastric pathogen Helicobacter pylori involves the oral route. Molecular techniques have allowed the detection of H. pylori DNA in samples of the oral cavity, although culture of H. pylori from these type of samples has been sporadic. Studies have tried to demonstrate the presence of H. pylori in adenotonsillar tissue, with contradictory results. Our aim was to clarify whether ...


Helicobacter pylori colonization of the adenotonsillar tissue: fact or fiction?

Vilarinho, S; Guimarães, NM; Ferreira, RM; Gomes, B; Wen, XG; Vieira, MJ; Carneiro, F; Godinho, T; Figueiredo, C

OBJECTIVE: The transmission of the gastric pathogen Helicobacter pylori involves the oral route. Molecular techniques have allowed the detection of H. pylori DNA in samples of the oral cavity, although culture of H. pylori from these type of samples has been sporadic. Studies have tried to demonstrate the presence of H. pylori in adenotonsillar tissue, with contradictory results. Our aim was to clarify whether ...

Data: 2010   |   Origem: Repositório Comum

A key role for Na+/K+-ATPase in the endothelium-dependent oscillatory activity ...

Giachini,F.R.C.; Carneiro,F.S.; Lima,V.V.; Carneiro,Z.N.; Brands,M.W.; Webb,R.C.; Tostes,R.C.

Oscillatory contractile activity is an inherent property of blood vessels. Various cellular mechanisms have been proposed to contribute to oscillatory activity. Mouse small mesenteric arteries display a unique low frequency contractile oscillatory activity (1 cycle every 10-12 min) upon phenylephrine stimulation. Our objective was to identify mechanisms involved in this peculiar oscillatory activity. First-orde...

Data: 2009   |   Origem: OASIS br

Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary dif...

Oliveira, C; Sousa, S; Pinheiro, H; Karam, R; Bordeira-Carriço, R; Senz, J; Kaurah, P; Carvalho, J; Pereira, R; Gusmão, L; Wen, X; Cipriano, MA

BACKGROUND & AIMS: Hereditary diffuse gastric cancer (HDGC) families carry CDH1 heterozygous germline mutations; their tumors acquire complete CDH1 inactivation through "2nd-hit" mechanisms. Most frequently, this occurs via promoter hypermethylation (epigenetic modification), and less frequently via CDH1 mutations and loss of heterozygosity (LOH). We quantified the different 2nd hits in CDH1 occurring in neopla...


H. pylori colonization of the adenotonsillar tissue : fact or fiction?

Vilarinho, S.; Ferreira, R. M.; Guimarães, N.; Gomes, B.; Xiaogang, W.; Oliveira, F.; Freitas, D.; Rodrigues, B.; Atraca, E.; Pereira, G.; Marçal, N.

Gastric infection with Helicobacter pylori is the most common chronic infection worldwide. One of the routes of transmission of the infection is the oral route. Molecular techniques have allowed the detection of H. pylori DNA in samples of the oral cavity, although culture of H. pylori from these types of samples has been sporadic. Studies have tried to demonstrate the presence of H. pylori in adenotonsillar ti...


Heat transfer evaluation on industrial pneumatic cylinders

J. F. Carneiro; F. Gomes de Almeida

Automatic positioning devices are worldwide used in tasks like handling or assembly, making them key components of modern manufacturing systems. Pneumatic solutions are usually less expensive than their electrical counterparts, are more reliable and require less maintenance. However, the complex nonlinear nature and high model order of pneumatic systems lead to a very difficult control task. These problems mak...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia