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Effect of cyclosporin-A on the blood-retinal barrier permeability in streptozot...
Carmo, Anália; Cunha-Vaz, José G.; Carvalho, Arsélio P.; Lopes, Maria CelesteBACKGROUND: Our previous results showed that in retinas from streptozotocin (STZ)-induced diabetic rats there is an increased level of interleukin-1beta (IL-1beta). This cytokine may be involved in the expression of the inducible isoform of the nitric oxide synthase (iNOS), with consequent synthesis of large amounts of NO and blood-retinal barrier (BRB) breakdown. AIMS: The aim of this work was to examine wheth...
Breakdown of the Inner and Outer Blood Retinal Barrier in Streptozotocin-Induce...
Carmo, Anália do; Ramos, Pedro; Reis, Aldina; Proença, Rui; Cunha-Vaz, J. G.Using vitreous fluorophotometry and quantitative fluorescence microscopy the authors studied the permeability of the blood-retinal barrier (BRB) to fluorescein in control and in 8 days streptozotocin-induced diabetic rats. ; http://www.sciencedirect.com/science/article/B6WFD-45JC7TK-T/1/ad834a7e41da87410003af7710548c3d
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