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Virgin olive oil as a source of anti-inflammatory agents
Cardoso, Susana M.; Catarino, Marcelo D.; Semião, Marta S.; Pereira, Olívia R.Virgin olive oil (VOO) has many potential health benefits, including the amelioration of inflammatory processes. In part, this is known to occur through the modification of the endothelial function, leading to a decrease of the levels of cell-adhesion molecules (CAMs), including the inter-cellular adhesion molecule 1 (ICAM-1) and the vascular cell adhesion molecule 1 (VCAM-1). Importantly, virgin olive oil is a...
Antioxidant activities of five Lamiaceae plants
Pereira, Olívia R.; Perez, Maria J.; Macias, Rócio I.R.; Marín, Jose J.G.; Cardoso, Susana M.In the last decades, oxidative stress has been recognized as a key process in the physiopathology of several diseases. Consequently, the search for new antioxidant compounds, as well as new antioxidant sources, has increased exponentially. The Lamiaceae family encloses many plant species which are potential sources of antioxidant compounds. The present study evaluates the antioxidant activity of phenolic enrich...
Protective effects of phenolic constituents from Cytisus multiflorus, Lamium al...
Pereira, Olívia R.; Macias, Rócio I.R.; Perez, María J.; Marín, Jose J.G.; Cardoso, Susana M.The present study investigated the antioxidant and cytoprotective effects of purified ethanolic extracts of Cytisus multiflorus, Lamium album L. and Thymus citriodorus plants. These extracts showed high antioxidant activity in DPPH and reducing power assays. Using a model of chemical stress induced by potassium dichromate (DK) in human hepatoblastoma HepG2 cells, 50 ug/mL of C. multiflorus, L. album and T. citr...
Overview on mentha and thymus polyphenols
Pereira, Olívia R.; Cardoso, Susana M.Mentha and Thymus are important genera of the Lamiaceae family widely distributed in the entire World and commonly used in traditional medicine. Indeed, many species of the two genera have been credited with a large list of health-benefit effects, including antioxidant, anti-inflammatory, antimicrobial, analgesic, neuroprotective and anticarcinogenic. In turn, these properties have been associated to the polyph...
Simultaneous characterization and quantification of phenolic compounds in Thymu...
Pereira, Olívia R.; Peres, António M.; Silva, Artur M.S.; Domingues, M.R.M.; Cardoso, Susana M.Thymus x citriodorus is a Lamiaceae plant extensively cultivated in Mediterranean region and used for centuries in culinary and in traditional medicine. The present work describes the detailed phenolic composition of T. x citriodorus for the first time, the by means of HPLC-DAD, ESI-MS and MSn and nuclear magnetic resonance (NMR) analyses. The ethanolic extract of T. x citriodorus was analyzed by reversed phase...
Phenolic constituents of lamium album: focus on isoscutellarein derivatives
Pereira, Olívia R.; Domingues, M.R.M.; Silva, Artur M.S.; Cardoso, Susana M.Lamium album L. is an edible plant which is consumed raw or cooked, in particular in the Mediterranean and surrounding areas. It is also consumed as tea infusions and as a main component of food supplements, because of its pharmacological effects. Despite being consumed by humans for centuries, the chemical composition of L album L is far from being understood. In this study, a purified ethanolic extract (PEEL)...
Cytisus multiflorus: source of antioxidant polyphenols
Pereira, Olívia R.; Perez, María J.; Macias, Rócio I.R.; Domingues, M.R.M.; Silva, Artur M.S.; Marín, Jose J.G.; Cardoso, Susana M.The present study investigates the phenolic composition and the antioxidant capacity of an ethanolic extract from flowers of C. multiflorus. As determined by HPLC-DAD, ESI-MSn and NMR combined analysis, this extract was mainly composed of chrysin-7-O-β-D-glycopyranoside, and also contained considerable amounts of rutin, a dihydroxyflavone isomer of chrysin and glycosidic derivatives of luteolin and apigenin. Th...
Cytisus multiflorus: source of antioxidant polyphenols
Pereira, Olívia R.; Perez, María J.; Macias, Rócio I.R.; Domingues, M.R.M.; Silva, Artur M.S.; Marín, Jose J.G.; Cardoso, Susana M.The present study investigates the phenolic composition and the antioxidant capacity of an ethanolic extract from flowers of C. multiflorus. As determined by HPLC-DAD, ESI-MSn and NMR combined analysis, this extract was mainly composed of chrysin-7-O-β-D-glycopyranoside, and also contained considerable amounts of rutin, a dihydroxyflavone isomer of chrysin and glycosidic derivatives of luteolin and apigenin. Th...
Novel flavones in Lamium L. genus
Pereira, Olívia R.; Domingues, M.R.M.; Silva, Artur M.S.; Cardoso, Susana M.The main aim of this work is to determine the phenolic composition of a Lamium album L. purified extract, in order to contribute for the chemical characterization of this plant. Moreover, it also intends to emphasize its antioxidant properties. As established by HPLC-DAD and ESI-MSn combined analysis, verbascoside was the major phenolic constituent of Lamium album L. purified extract, as previously described by...
Cytisus multiflorus: source of antioxidant polyphenols
Pereira, Olívia R.; Perez, María J.; Macias, Rócio I.R.; Domingues, M.R.M.; Silva, Artur M.S.; Marín, Jose J.G.; Cardoso, Susana M.The present study investigates the phenolic composition and the antioxidant capacity of an ethanolic extract from flowers of C. multiflorus. As determined by HPLC-DAD, ESI-MSn and NMR combined analysis, this extract was mainly composed of chrysin-7-O-β-D-glycopyranoside, and also contained considerable amounts of rutin, a dihydroxyflavone isomer of chrysin and glycosidic derivatives of luteolin and apigenin. Th...
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