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Tf-lipoplexes for neuronal siRNA delivery: A promising system to mediate gene s...
Cardoso, A. L. C.; Simões, S.; Almeida, L. P. de; Plesnila, N.; Lima, M. C. Pedroso de; Wagner, E.; Culmsee, C.http://www.sciencedirect.com/science/article/B6T3D-4TBXG8W-1/2/0126aa3460b30ae6bbcf04124c1c63dd
Data: 2008
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Origem: Estudo Geral - Universidade de Coimbra
siRNA delivery by a transferrin-associated lipid-based vector: a non-viral stra...
Cardoso, A. L. C.; Simões, S.; Almeida, L. P. de; Pelisek, J.; Culmsee, C.; Wagner, E.; Lima, M. C. Pedroso deRNA interference provides a powerful technology for specific gene silencing. Therapeutic applications of small interfering RNA (siRNA) however require efficient vehicles for stable complexation, protection, and extra- and intracellular delivery of these nucleic acids. Here, we evaluated the potential of transferrin (Tf)-associated liposomes for siRNA complexation and gene silencing.Cationic liposomes composed o...
Data: 2007
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Origem: Estudo Geral - Universidade de Coimbra
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