The global tuberculosis (TB) threat is diffi cult to evaluate in countries with scarce laboratory facilities where little is known about the genetic basis of drug resistance, including the rpoB RRDR (rifampicin resistance determining region) of the Mycobacterium tuberculosis complex (MTC). The present study aimed at performing a preliminary evaluation of rpoB polymorphisms in a DNA set of MTC isolates from Guin...
The release of the opioid antagonist naltrexone from neutral poly(N-isopropylacrylamide) (PNIPAAM)microgels and negatively charged PNIPAAM microgels containing acrylic acid groups (PNIPAAM-co-PAA) has been studied at various microgel and drug concentrations. The release curves were found to be well represented by the Weibull equation. The release rates were observed to be dependent on the microgel concentration...
The diagnosis of tuberculosis is seriously hampered in the absence of standard biosafety laboratory facilities for specimen concentration and Mycobacterium tuberculosis culture. Within a laboratory twinning arrangement,heat-fixed direct smear and sediment from 74 bleach-processed and 20 non-processed specimens from Cumura Hospital, Guinea-Bissau, were sent to Lisbon for molecular evaluation of rifampicin resist...
This paper presents a new scheme for power transformers differential protection, in which the concept of the Park's instantaneous differential powers is introduced. The proposed method is able to detect winding insulation failures and to distinguish them from magnetizing inrush current transients. Experimental and simulation results are presented and discussed.
This paper presents the application of the on-load exciting current Extended Park's Vector Approach to diagnose incipient turn-to-turn winding faults in operating power transformers. Experimental and simulation test results demonstrate the effectiveness of the proposed technique, which is based on the spectral analysis of the AC component of the on-load exciting current Park's Vector modulus.
O fisioterapeuta, enquanto profissional de saúde envolvido na promoção e educação para a saúde, e apresentando funções de aconselhamento, poderá, no exercício da sua prática clínica, aconselhar medicamentos aos seus utentes, para além da eventual administração dos mesmos. No entanto, e apesar dessas práticas, o fisioterapeuta tem na maior parte dos casos pouca formação na área da farmacologia. O aconselhamento ...
Os pacientes com doença hemato-oncológica submetidos a quimioterapia possuem maior propensão para infecções bacterianas. O seu diagnóstico pode ser efectuado recorrendo-se aos marcadores biológicos: procalcitonina (PCT) e proteína C reactiva (PCR). Neste estudo, observaram-se diferenças estatisticamente significativas na concentração de PCT nos diferentes grupos de infecção, o que não se verificou na concentraç...
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