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Value of patch tests in clindamycin-related drug eruptions

Pereira, N; Canelas, MM; Santiago, F; Brites, MM; Gonçalo, Margarida

Background. Patch tests help to confirm the aetiology of the cutaneous adverse drug reactions involving delayed hypersensitivity mechanisms, but the results vary with the pattern of skin reaction and the culprit drug. Objectives. To analyse the results of patch tests in patients with cutaneous adverse drug reactions imputable to clindamycin and assess their contribution to the diagnosis. Patients and methods. B...


Fibrous histiocytomas: histopathologic review of 95 cases.

Canelas, MM; Cardoso, JC; Andrade, PF; Reis, JP; Tellechea, O

Fibrous histiocytoma (FH) is a heterogeneous tumor composed of fibroblasts, histiocytes, and blood vessels. We conducted a retrospective histopathologic analysis of 95 biopsies, performed over the last 3.5 years, of fibrous histiocytomas to analyze the location, delimitation, epithelial changes, induction of folliculo-sebaceous structures, cellularity, vascularity, collagen pattern, and types of composite cells...


Photoallergic contact dermatitis from benzydamine presenting mainly as lip derm...

Canelas, MM; Cardoso, JC; Gonçalo, Margarida; Figueiredo, A

BACKGROUND: Benzydamine, a non-steroidal anti-inflammatory drug (NSAID) in use for more than four decades, has been reported to cause photosensitivity. OBJECTIVES: To study the results of photopatch testing to benzydamine and the clinical features of the dermatitis during a 3-year period (2006-2008). PATIENTS AND METHODS: During this period, 74 patients with photodermatoses were photopatch tested with an exte...



Photopatch testing with an extended series of photoallergens: a 5-year study

Cardoso, JC; Canelas, MM; Gonçalo, Margarida; Figueiredo, A

OBJECTIVE: We conducted a retrospective study (2003-07) evaluating the results of photopatch tests (PPTs) performed with an extended series with the objective of determining the main photoallergens in our region and whether they would be detected by a recently recommended baseline PPT series. MATERIALS AND METHODS: 83 patients (58 females/25 males, mean age 54.8 years) were tested with a photoallergen series, a...


Síndrome de Hipersensibilidade a Fármacos / DRESS: 5 Anos de Experiência num Se...

Santiago, F; Cravo, M; Cardoso, JC; Canelas, MM; Vieira, R; Gonçalo, Margarida; Figueiredo, A


Dermatite de contacto fotoalérgica à benzidamina: estudo de 8 casos

Canelas, MM; Cravo, M; Cardoso, JC; Gonçalo, Margarida; Figueiredo, A


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia